Retrospective Analysis of Risk Factors of Acute Respiratory Failure After Esophageal Cancer Surgery
Objective To analyze the risk factors of acute respiratory failure after esophageal cancer surgery.Methods From January to December 2022,178 patients who were diagnosed as esophageal cancer by relevant examinations in the Fujian Cancer Hospital were retrospectively studied.All patients were treated with three-field radical resection of esophageal cancer,the incidence of postoperative acute respiratory failure was counted,the risk factors of acute respiratory failure after esophageal cancer surgery were analyzed.Results Among 178 patients with esophageal cancer,17 cases(9.55%)developed acute respiratory failure after three-field radical resection of esophageal cancer,and 161 cases(90.45%)did not develop acute respiratory failure.Univariate analysis showed that there were significant differences in age,smoking history,TNM stage,diabetes mellitus,surgical method,postoperative secondary thoracotomy,pulmonary infection,plasma albumin and pain between the two groups(P<0.05).Multivariate logistic analysis showed age≥70 years old(OR=1.414,P=0.044),history of smoking(OR=1.441,P=0.026),TNM stage Ⅱ-Ⅲ(OR=1.645,P<0.001),combined with diabetes(OR=1.671,P<0.001),secondary thoracotomy(OR=1.384,P=0.021),pulmonary infection(OR=1.841,P<0.001),plasma albumin>25 g/L(OR=1.376,P=0.005),moderate to severe pain(OR=1.541,P<0.001)were risk factors for acute respiratory failure after esophageal cancer surgery(P<0.05).Conclusion The incidence of acute respiratory failure after esophageal cancer surgery is high.In order to improve its prognosis,it is necessary to strengthen the management of controllable factors in the perioperative period,and minimize the impact on treatment and prognosis effect.