Observation on the Effect of Endoscopic Submucosal Dissection in the Treatment of Early Gastric Cancer
Objective To study the therapeutic effect of submucosal dissection of early gastric cancer under digestive endoscopy.Method Sixty patients with early gastric cancer were selected from Fujian Provincial Geriatric Hospital,with a time range of January 2021 to June 2022.The grouping method was a randomized double-blind method.The control group consisted of 30 cases treated with submucosal resection under digestive endoscopy,while the observation group consisted of 30 cases treated with submucosal dissection under digestive endoscopy.Results The complete resection rate and curative resection rate of early gastric cancer patients in the observation group were higher than those in the control group(χ2=4.043,7.051,P<0.05).The surgical time and intraoperative blood output of early gastric cancer patients in the observation group were higher than those in the control group(t=12.742,14.581,P<0.05),while the recovery time and hospitalization time of gastrointestinal function were lower than those in the control group(t=15.320,7.297,P<0.05).After treatment of early gastric cancer patients,the levels of CA125 and CA199 in the observation group were lower than those in the control group(t=9.182,6.706,P<0.05);the levels of motilin and pepsinogen I were higher in the control group(t=10.55,6.492,P<0.05).The total incidence of complications in the observation group was significantly lower than that in the control group(χ2=4.342,P<0.05).The recurrence rate of early gastric cancer patients in the observation group(3 months after surgery)was slightly lower than that in the control group(χ2=1.724,P>0.05);the recurrence rate(6 months after surgery)was significantly lower than that of the control group(χ2=4.064,P<0.05).Conclusion Early gastric cancer patients are treated with endoscopic submucosal dissection,which has a significantly better therapeutic effect than endoscopic submucosal resection.It can be seen that endoscopic submucosal dissection has significant advantages and more promotional value.
early gastric cancerdigestive endoscopysubmucosal dissectiontumor markersgastrointestinal functionrecurrence rate
万方数据
维普
