The Efficacy of Octreotide and Pantoprazole in the Treatment of Peptic Ulcer Complicated With Upper Gastrointestinal Bleeding
Objective To explore the efficacy of octreotide combined with pantoprazole in the treatment of peptic ulcer complicated with upper gastrointestinal bleeding.Methods A total of 70 patients with peptic ulcers complicated with upper gastrointestinal bleeding who received treatment at Ningde Municipal Hospital of Ningde Normal University from May 2018 to December 2020 were divided into an observation group and a control group,with 35 cases in each group.The treatment efficacy and levels of related inflammatory factors between two groups of patients were compared.Results The effective rate of treatment in the observation group was 97.14%,significantly higher than 82.85%in the control group,with a significant statistical difference(P<0.05).The number of black stools(0.60±0.19)times,hemostasis time(0.43±0.13)d,and abdominal pain relief time(0.45±0.15)d in the observation group were significantly lower than those in the control group(1.34±0.53)times,(1.06±0.42)days,and(1.15±0.54)d(P<0.05).In terms of inflammatory level,the level of inflammatory factors statistical difference(P<0.05).Both groups of patients did not experience any related adverse reactions.Conclusion For digestive complications with upper gastrointestinal bleeding,the efficacy of monotherapy(pantoprazole)is not ideal,but the comprehensive effect based on combination therapy(octreotide and pantoprazole)is more ideal,itcan effectively control bleeding,improve related symptoms,and improve blood routine and inflammatory levels more significantly..
万方数据
维普
