Application of Two Image Registration Techniques in Intensity Modulated Radiotherapy for Brain Metastases
Objective To explore the application of image scout(Iscout)and KV cone beam CT(CBCT)in intensity modulated radiotherapy for brain metastasies.Methods A total of 124 patients with brain metastases treated with radiotherapy in department of radiotherapy,Zhangzhou Affiliated Hospital of Fujian Medical University from November 2020 to November 2022 were selected.Among them,62 patients were treated with CBCT image guidance technology and were set as CBCT group,and 62 patients were treated with Iscout and were set as Iscout group.The translation errors,positioning time and MPTV values of the two groups were observed.Results The positioning errors in the scanning direction of right-left(RL),superior-inferior(SI)and anterior-posterior(AP)in the CBCT group are compared with those in the Iscout group,and the difference was not statistically significant(P>0.05).There was no significant difference in scanning preparation time between the two groups(P>0.05).The exposure time,registration time and total positioning time of CBCT group were(21.76±5.06)s,(81.64±7.59)s and(210.52±4.06)s,respectively,which were longer than those of Iscout group(12.89±3.09)s,(65.41±6.35)s and(141.49±3.35)s,the difference was statistically significant(P<0.05).The MPTV of the CBCT group in the RL,SI,and AP directions is 7.02,10.43,and 8.13 mm,respectively.The MPTV of the Iscout group in the RL,SI,and AP directions is 7.15,10.57,and 8.19 mm,respectively.The expandable boundary of the CBCT group is 2.1 mm smaller than that of the Iscout group in the SI direction,and there is no significant difference in the expandable area calculated by the two groups in the RL and AP directions.Conclusion During intensity-modulated radiotherapy for patients with brain metastasies,both image guided positioning techniques can correct the positioning errors.CBCT image guided positioning technology has high spatial resolution,but the total positioning time is longer,while Iscout image guided positioning technology can enable patients to obtain fast,accurate and low-dose positioning verification,thus significantly increasing the safety and clinical effects of treatment.
万方数据
维普
