Assessment of the Condition and Short-Term Prognosis of Elderly Patients With Acute Respiratory Distress Syndrome by EVLWI
Objective To analyze the predictive effect of extravascular lung water index(EVLWI)on the condition and short-term prognosis of elderly patients with acute respiratory distress syndrome(ARDS).Methods A total of 60 elderly patients with ARDS admitted to department of intensive care medicine,the Affiliated Hospital of Putian University from May 2020 to May 2022 were included as for observation.The patients were divided into 42 patients in the survival group and 18 patients in the sick-death group according to their survival status within 3 d after admission.Two groups of the baseline data[mainly include age,gender,the white blood cell(WBC)and acute physiology and chronic health evaluation scoring system(APACHE Ⅱ)score,etc.],different time points after admission EVLWI levels,cardiac index(CI),central venous pressure(CVP),mean artery pressure(MAP),oxygenation index level were compared.Multivariate logistic regression analysis was performed.Results The survival group of APACHE Ⅱ score compared with sick-death group was lower,the difference was statistically significant(P<0.05).The EVLWI of the survival group at 2 and 3 d after admission were(9.80±2.11)mL/kg and(7.41±1.52)mL/kg,respectively,which were lower than those of the sick-death group(15.07±2.74)mL/kg and(16.08±2.36)mL/kg,the difference was statistically significant(P<0.05).The survival group had lower CI level at 2 d and 3 d after admission than the sick-death group,while the oxygenation index at 2 d and 3 d after admission was higher than the sick-death group,the difference was statistically significant(P<0.05).In death as the dependent variable,APACHE Ⅱ score,EVLWI,CI,oxygenation index as the independent variable.The multi-factor logistic regression analysis available,APACHEⅡ score,EVLWI,CI were the independent risk factors of death in patients with ARDS elderly,and oxygenation index was the protective factors of death in patients with ARDS in elderly.Conclusion With the increase of EVLWI level,the risk of death in elderly patients with ARDS increases.We can further predict the patients'condition and short-term prognosis by dynamically monitoring the change trend of EVLWI.
acute respiratory distress syndromeextravascular lung water indexpatients'conditionshort-term prognosisprediction functionelderly patients