Effect of Different Treatment Time Window on Emergency Coronary Intervention in Patients With Acute Anterior Myocardial Infarction
Objective To explore the impact of emergency coronary intervention treatment on the efficacy of acute anterior wall myocardial infarction at different treatment time windows.Methods A total of 140 patients with acute anterior wall myocardial infarction who underwent emergency coronary intervention treatment at Affiliated Hospital of Jiangnan University from January 2021 to December 2022 were selected.Among them,70 patients had a duration of<3 hours from onset to emergency coronary intervention treatment as the<3 h group,and 70 patients had a duration of 3-8 h from onset to emergency coronary intervention treatment as the 3-8 h group.After operation,coronary angiography was reviewed to observe the improvement of the degree of stenosis of the diseased vessels and evaluate the therapeutic effect.Results The total effective rate of the<3 h group(98.57%,69/70)was higher than that of the 3-8 h group(84.29%,59/70)(P<0.05).The levels of myocardial damage indicators in the<3 h group after treatment were lower than those in the 3-8 h group(P<0.05).The left ventricular end systolic diameter,left ventricular end diastolic diameter,and left atrial diameter in the<3 h group were lower than those in the 3-8 h group(P<0.05).After treatment,the left ventricular ejection fraction(52.36±4.24)%and early diastolic peak blood flow velocity of mitral valve opening/late diastolic peak blood flow velocity(E/A)(1.33±0.18)were higher than those in the 3-8 h group[(47.13±5.16)%,(1.29±0.20)](P<0.05).Following up for 6 months,no deaths were found in both groups.The incidence of adverse cardiovascular events such as angina,arrhythmia,and cardiogenic shock in the<3 h group was lower than that in the 3-8 h group(P<0.05).Conclusion Early implementation of coronary intervention therapy after acute anterior wall myocardial infarction can improve the patient's prognosis and clinical outcomes.
万方数据
维普
