首页|鼻咽癌同步放化疗自评口腔黏膜炎与自我管理积极度的相关性研究

鼻咽癌同步放化疗自评口腔黏膜炎与自我管理积极度的相关性研究

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目的 了解鼻咽癌(nasopharyngeal carcinoma,NPC)同步放化疗自评口腔黏膜炎情况、自我管理积极度现状,探讨两者之间的关系,并分析NPC患者自评口腔黏膜炎的影响因素。方法 采用方便抽样法,选取 2023 年 6-9 月中山大学肿瘤防治中心处于同步放化疗期间的NPC患者作为研究对象。使用一般资料调查表、口腔黏膜炎每日自评问卷(oral mucositis daily questionnaire,OMDQ)、患者积极度量表(patient activation measure,PAM)对 115 例患者进行调查。采用Pearson相关分析、单因素检验及多重线性回归统计分析,探讨NPC患者同步放化疗期间口腔黏膜炎的影响因素。结果 NPC同步放化疗患者OMDQ为(12。61±6。75)分,得分排名前 3 的条目依次是感觉自己整体健康状况、口腔清洁舒适状况及进食类型。患者PAM得分为(83。93±5。79)分,总体在高水平。相关分析显示,PAM得分与OMDQ总分呈负相关(r=-0。619,P<0。001)。多元线性回归显示,是否远处转移、放疗次数及患者积极度水平是该群体口腔黏膜炎的影响因素,共解释总变异水平的 55。5%(P<0。001)。结论 NPC患者同步放化疗期间口腔黏膜炎管理需加强,患者积极度水平与口腔黏膜炎呈负相关,应帮助患者做好口腔管理,调动患者参与疾病管理的积极性,增强患者自我管理的信心,帮助患者积极应对现存症状和疾病。
Correlation Between Daily Self-Measurement of Oral Mucositis and Patient Activation in Nasopharyngeal Carcinoma Patients Undergoing Radiochemotherapy
Objective To investigate the the current situation of self-measurement oral mucositis and patient activation in patients with nasopharyngeal carcinoma(NPC)undergoing radiochemotherapy,and to explore the relationship between them,analyze its influencing factors in NPC patients.Methods NPC patients who were undergoing concurrent chemoradiation and chemotherapy in Sun Yat-Sen University Cancer Center from June to September 2023 were selected as the study objects by convenient sampling method.A total of 115 patients were investigated by general data questionnaire,oral mucositis daily questionnaire(OMDQ)and patient activation measure(PAM).Pearson correlation analysis,single factor test and multiple linear regression statistical analysis were used to investigate the influencing factors of oral mucositis in NPC patients during concurrent chemoradiotherapy.Results The OMDQ of NPC patients with concurrent chemoradiotherapy was(12.61±6.75)points,and the top three items were self-perceived overall health status,oral cleaning and comfort status,and eating type.The PAM score of the patient was(83.93±5.79)points,which was high level.Correlation analysis showed that PAM score was negatively correlated with the total score of OMDQ(r=-0.619,P<0.001).Multiple linear regression showed that whether distant metastasis,the number of radiotherapy and the level of patient activeness were the influencing factors of oral catarrh in this population,accounting for 55.5%of the total variation(P<0.001).Conclusion The management of oral mucositis in NPC patients during radiochemotherapy needs to be strengthened,and there is a negative correlation between patients'activation level and oral mucositis.Patients should be helped to do oral management well,mobilize their enthusiasm to participate in disease management,enhance their confidence in self-management,and help them actively cope with existing symptoms and diseases.

oral mucositisnasopharyngeal carcinomaradiochemotherapypatient activationself-assessmentcorrelation study

侯敏、曾雪辉、陈娴、林家驹、冯惠霞

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中山大学肿瘤防治中心放疗科,广东 广州 510060

口腔黏膜炎 鼻咽癌 同步放化疗 积极度 自我评估 相关性研究

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(2)
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