Objective To investigate the the current situation of self-measurement oral mucositis and patient activation in patients with nasopharyngeal carcinoma(NPC)undergoing radiochemotherapy,and to explore the relationship between them,analyze its influencing factors in NPC patients.Methods NPC patients who were undergoing concurrent chemoradiation and chemotherapy in Sun Yat-Sen University Cancer Center from June to September 2023 were selected as the study objects by convenient sampling method.A total of 115 patients were investigated by general data questionnaire,oral mucositis daily questionnaire(OMDQ)and patient activation measure(PAM).Pearson correlation analysis,single factor test and multiple linear regression statistical analysis were used to investigate the influencing factors of oral mucositis in NPC patients during concurrent chemoradiotherapy.Results The OMDQ of NPC patients with concurrent chemoradiotherapy was(12.61±6.75)points,and the top three items were self-perceived overall health status,oral cleaning and comfort status,and eating type.The PAM score of the patient was(83.93±5.79)points,which was high level.Correlation analysis showed that PAM score was negatively correlated with the total score of OMDQ(r=-0.619,P<0.001).Multiple linear regression showed that whether distant metastasis,the number of radiotherapy and the level of patient activeness were the influencing factors of oral catarrh in this population,accounting for 55.5%of the total variation(P<0.001).Conclusion The management of oral mucositis in NPC patients during radiochemotherapy needs to be strengthened,and there is a negative correlation between patients'activation level and oral mucositis.Patients should be helped to do oral management well,mobilize their enthusiasm to participate in disease management,enhance their confidence in self-management,and help them actively cope with existing symptoms and diseases.
关键词
口腔黏膜炎/鼻咽癌/同步放化疗/积极度/自我评估/相关性研究
Key words
oral mucositis/nasopharyngeal carcinoma/radiochemotherapy/patient activation/self-assessment/correlation study
维普
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