首页|基于孕中期临床资料构建子痫前期疾病预测模型的研究

基于孕中期临床资料构建子痫前期疾病预测模型的研究

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目的 探讨孕中期临床资料对构建子痫前期疾病的预测价值。方法 选取 2019 年 1 月—2022 年 12 月济宁市第三人民医院 275 例妊娠期孕妇为研究对象,105 例子痫前期患者作为子痫前期组,170 例妊娠妇女为对照组。通过logistic回归分析、nomogram图、受试者操作特征(receiver operating characteristics,ROC)曲线等方法构建预测模型。结果 2 组年龄、孕次、产次、流产、存活子女、经产妇、不良孕产史、剖宫产史、身高等差异无统计学意义(P>0。05);经logistic回归分析,身体质量指数(body mass index,BMI)、国际标准化比值(International standard ratio,INR)、纤维蛋白原(fibrinogen,FIB)、舒张压是子痫前期高危风险因素,差异有统计学意义(P<0。05);经ROC曲线、nomogram图分析,BMI、FIB、白蛋白、舒张压能用于诊断子痫前期,差异有统计学意义(P<0。05)。结论 孕中期BMI、FIB、白蛋白、舒张压对子痫前期疾病的诊断具有一定预测作用。
Research on Constructing a Predictive Model for Preeclampsia Based on Clinical Data in the Second Trimester of Pregnancy
Objective To explore the predictive value of clinical data in the second trimester of pregnancy for constructing preeclampsia diseases.Methods A total of 275 pregnant women during pregnancy of the Third People's Hospital of Ji′ning from January 2019 to December 2022 were selected as the study subjects,and 105 women with preeclampsia were selected as the observation group.Another 170 pregnant women were selected as the control group,and the prediction model was constructed by logistic regression analysis,nomogram,Receiver operating characteristic and other methods.Results There was no significant difference in age,pregnancy,birth,abortion,surviving children,multipara,history of adverse pregnancy,history of Caesarean section,and height(P>0.05).Through logistic regression analysis,body mass index(BMI)、International standard ratio(INR)、fibrinogen(FIB),and diastolic blood pressure were high-risk factors for preeclampsia,with statistically significant differences(P<0.05).According to Receiver operating characteristic and nomogram analysis,BMI,FIB,albumin and diastolic blood pressure can be used to diagnose preeclampsia,and the difference is statistically significant(P<0.05).Conclusion BMI,FIB,albumin,and diastolic blood pressure in mid pregnancy have certain predictive effects on the diagnosis of preeclampsia.

clinical datasecond trimesterpreeclampsiapredictive modelmultiparturientcesarean section

张翠焕、满冬梅

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济宁市第三人民医院妇产科,山东 济宁 272100

临床资料 孕中期 子痫前期 预测模型 经产妇 剖宫产

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(3)
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