Analysis of Drug Resistance of Main Bacteria in a Hospital From 2020 to 2022
Objective To analyse the drug resistance of common bacteria in the Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine Hospital from 2020 to 2022,we can understand the situation of bacterial drug resistance in our hospital,and provide reference for rational use of antibiotics in clinic.Methods The pathogenic strains isolated from patients in the Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine from 2020 to 2022 were statistically analyzed by retrospective analysis,and the distribution,species and drug resistance of pathogenic bacteria were analyzed.Results From 2020 to 2022,a total of 12009 strains were isolated,and respiratory specimens(including sputum and alveolar lavage fluid)were the most.The top 5 were Escherichia coli 2139 strains(17.81%),Klebsiella pneumoniae 1342 strains(11.17%),Pseudomonas aeruginosa 1094 strains(9.11%),Staphylococcus aureus 793 strains(6.60%)and Acinetobacter baumannii 541 strains(4.50%).CR-KP(Carbapenem-resistant Klebsiella pneumoniae)and CR-PA(Carbapenem-resistant Pseudomonas aeruginosa)were significantly higher in 2022 than in 2020,and the differences were statistically significant(P<0.01).There was no significant difference in the detection rates of the other three types of MRSA(Methicillin-resistant Staphylococcus aureus),CR-EC(Carbapenem-resistant Escherichia coli)and CRAB(Carbapenem-resistant Acinetobacter baumannii)during the three years(P>0.05).The resistance rate of Acinetobacter baumannii to most common antibiotics is more than 50%.Conclusion The main bacteria in the Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine are gram-negative bacilli,the resistance rate of Acinetobacter baumannii to most common antibiotics is more than 50%,and the resistance rate of CR-KP(Carbapenem-resistant Klebsiella pneumoniae)and CR-PA(Carbapenem-resistant Pseudomonas aeruginosa)shows an increasing trend.It is recommended to pay close attention to the change of drug resistance of pathogenic bacteria to reduce the occurrence of multi-drug resistant bacteria.
bacterial drug resistanceantimicrobial drugsCarbapenemresistant K.pneumoniaeCarbapenemresistant Pseudomonas aeruginosadrug resistance ratemultiple drug resistance
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