首页|骨质疏松症影响股骨转子间骨折PFNA术后髋关节恢复的研究

骨质疏松症影响股骨转子间骨折PFNA术后髋关节恢复的研究

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目的 探讨骨质疏松症能否影响股骨转子间骨折股骨近端防旋髓内钉(proximal femoral nail antirotation,PFNA)术后患者髋关节功能的恢复。方法 选取 2021 年 1 月 1 日—2022年 9 月 1 日在海安市中医院骨伤科诊断为股骨转子间骨折行PFNA手术并符合相关标准的 115 例患者纳入研究,分为对照组 49 例与骨质疏松症组 66 例。各组患者均行PFNA手术治疗,术后通过电话随访和主动告知的形式记录术后患者下肢功能恢复时间。生存分析Kaplan-Meier法计算术后患者下肢功能恢复的中位时间和 95%可信区间(confidence interval,CI),采用Breslow和Log-Rank法比较 2 组下肢功能恢复时间差异;以多因素Cox回归分析影响术后患者下肢功能恢复速度的因素。结果 对照组髋关节功能恢复中位时间为13。84 d,95%CI 12。91~14。78 d,骨质疏松症组髋关节功能恢复中位时间为 16。94 d,95%CI 15。99~17。89 d,差异有统计学意义(P<0。001)。Cox回归分析发现骨质疏松症对术后下肢功能恢复时间有影响(HR= 0。265,95%CI 0。172~0。410,P<0。001)。结论 骨质疏松症可延缓股骨粗隆间骨折PFNA术后患者的临床愈合时间,而抗骨质疏松药物可能并无影响。
Study on the Investigation of Osteoporosis Affecting the Hip Joint Recovery for the Intertrochanteric Fracture Patients With PFNA Operation
Objective To investigate the effect of osteoporosis on the hip joint recovery for the intertrochanteric fracture patients with proximal femoral nail antirotation(PFNA)operation.Methods A total of 115 patients diagnosed with intertrochanteric fracture of femur and receiving PFNA surgery in the department of orthopedics and traumatology,Hai'an Municipal TCM Hospital from January 1,2021 to September 1,2022,who met relevant criteria,were included in the study,and were divided into 49 patients in the control group and 66 patients in the osteoporosis group.All the patients received the operation of PFNA.The recovery times of lower limb were gotten by telephone reviews of the doctors or active information of patients.Kaplan-Meier belonging to survival analysis methods was used to calculate the median recovery time of lower limb function and the 95%confidence interval(CI).With Breslow and Log-Rank methods,the recovery time difference between the groups was compared.Multiple factors Cox regression was applied to investigate the factors affecting the recovery time speed for the patients.Results The median recovery time of lower limb function for the control group was 13.84 d,95%CI 12.91 to 14.78 d,with 16.94 d,and 95%CI 15.99 to 17.89 d for the osteoporosis group,the difference was statistically significant(P<0.001).Cox model found osteoporosis had an effect on the recovery time of lower limb function(HR=0.265,95%CI 0.172 to 0.410,P<0.001).Conclusion Osteoporosis could delay the clinical recovery time of lower limb function for patients diagnosed as intertrochanteric fracture and suffering from PFNA operation.However,anti-osteoporosis drug might have no effect.

osteoporosisanti-osteoporosis drugsintertrochanteric fracturePFNAhip joint recoveryrecovery time

徐旭东、周永进、魏爱淳

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海安市中医院骨伤科,江苏 海安 226600

骨质疏松症 抗骨质疏松药物 股骨转子间骨折 PFNA 髋关节功能 恢复时间

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(4)
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