Clinical Comparative Study of Albumin and Gamma Globulin Assisted Blue Light Treatment of Neonatal Jaundice
Objective To explore the clinical comparison of albumin and gamma globulin assisted blue light treatment of neonatal hyperbilirubinemia.Methods A total of 65 newborns with hyperbilirubinemia admitted to the Wuzhou Maternal and Child Health-Care Hospital from January 2018 to December 2022 were selected.Based on their diagnostic results,they were divided into the immunoglobulin group(33 cases diagnosed with hyperbilirubinemia caused by ABO incompatible hemolytic disease in newborns)and the albumin group(32 cases diagnosed with hyperbilirubinemia caused by ABO incompatible hemolytic disease in newborns),The gamma globulin group received gamma globulin assisted blue light treatment,while the albumin group received albumin assisted blue light treatment.The clinical efficacy of two groups,serum total bilirubin(TBIL),indirect bilirubin(IBIL),and direct bilirubin(DBIL)levels,the incidence of adverse reactions were compared.Results Compared with the albumin group(84.38%),the clinical efficacy of the gamma globulin group(93.94%)was significantly higher than that of the albumin group,and the difference was statistically significant(P<0.05).Compared with before treatment,the serum TBIL,IBIL,DBIL levels of the two groups were significantly decreased after treatment,and the decrease range of the gamma globulin group was significantly greater than that of the control group,and the difference was statistically significant(P<0.05).Compared with the albumin group(12.50%),the incidence of adverse reactions(6.06%)in the globulin group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Albumin and gamma globulin assisted blue light therapy can effectively treat neonatal hyperbilirubinemia,but compared with albumin,gamma globulin assisted blue light therapy has more significant effect and fewer adverse reactions,which has certain clinical reference value.
万方数据
维普
