Serum Detection Effect and Detection Rate of Hemolytic Disease in Newborns With Hyperbilirubinemia
Objective To analyze the serum detection effect and detection rate of hemolytic disease in newborns with hyperbilirubinemia.Methods From August 2022 to July 2023,a total of 308 newborns with confirmed hyperbilirubinemia in department of blood transfusion,Meizhou People's Hospital were screened,their blood types were identified,and three serological tests were conducted,including elution test,dissociation test,and direct antibody test.The detection results were analyzed,the detection rate of hemolytic disease by each serum detection method was counted,the blood group distribution was analyzed,and the value of serum detection was evaluated.Results In the serum test for hemolytic disease,44.8%were positive in the diffusion test,1.9%were positive in the direct antibody test,and 29.2%were positive in the free test.The release test had the highest detection rate,followed by the free test and direct antibody test,with statistical significance(P<0.05).Among the children with neonatal hemolytic disease,the proportion of type A and type B blood was the highest,and the difference was statistically significant(P<0.05).Conclusion The risk of hemolytic disease is high in newborns with hyperbilirubinemia.By conducting three serum tests,the detection rate of hemolytic diseases can be effectively improved,making it convenient for targeted treatment.Mastering the blood type distribution characteristics of hemolytic diseases can also provide more comprehensive monitoring.
hyperbilirubinemianewbornshemolytic diseaseserum testingrelease testdissociation testdirect resistance test
万方数据
维普
