Correlation Analysis of Metabolic Syndrome With the Severity of HTG-AP
Objective To investigate the impact of metabolic syndrome(MS)on the severity of hypertriglyceridemic acute pancreatitis(HTG-AP)and the independent risk factors of HTG-AP in the metabolic syndrome group.Methods Retrospective selection of clinical data from patients with acute pancreatitis(AP)admitted to the Third People's Hospital of Hubei Province from January 2017 to May 2023 within 48 hours after onset,and screening of HTG-AP patients into mild,moderate,and severe categories.According to whether the patient has MS,they were divided into an MS group HTG-AP and a non MS group HTG-AP.Wilcoxon signed rank sum test was used to compare the severity grading of HTG-AP between the MS group and the non MS group with two independent samples.Multiple ordered logistic regression analysis was used to analyze the general data and independent risk factors of experimental indicators for HTG-AP with combined MS.Results A total of 597 cases of AP were collected,including 165 cases of HTG-AP and 89 cases of HTG-AP in the MS group[mild acute pancreatitis(MAP)54 cases,moderately severe acute pancreatitis(MSAP)20 cases,severe acute pancreatitis(SAP)15 cases].There were 76 cases of HTG-AP in the non MS group(MAP 61 cases,MSAP 12 cases,SAP 3 cases).A Wilcoxon signed rank sum test was used to compare two independent samples between the two groups,and it was found that there was a significant difference in severity grading between the two groups(P<0.05).Multiple ordered logistic regression analysis confirmed that fasting plasma glucose(FPG)and triglyceride(TG)were independent risk factors for HTG-AP in the MS group(P<0.05),with larger values indicating higher severity.Conclusion There was a significant difference in the severity grading between the MS group HTG-AP and the non MS group HTG-AP,and the severity of the MS group HTG-AP was higher than that of the non MS group HTG-AP.FPG and TG are independent risk factors for the severity of HTG-AP in patients with concomitant MS,and the larger their values,the higher the severity,which has certain clinical significance in predicting the severity of HTG-AP in patients with concomitant MS.
acute pancreatitismetabolic syndromehypertriglyceridemiaindependent risk factorsmodified Marshall scoringother types of pancreatitis
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