Preventive Effect of Dezocine on Urinary Catheter-Related Bladder Discomfort After General Anesthesia
Objective To investigate the preventive effect of dezocine on urinary catheter-related bladder discomfort(CRBD)after general anesthesia.Methods A total of 60 patients undergoing percutaneous nephrolithotomy under general anesthesia admitted to Haiyin Hospital the First Affiliated Hospital of Guangzhou Medical University from April 2022 to March 2023 were selected and divided into observation group and control group according to whether dizocine was injected before surgery.The control group was given 2 mL of normal saline intravenously 20 min before the end of the operation.Observation group received intravenous injection of dezocine 0.1 mg/kg 20 min before the end of operation.The pain degree of[visual analogue scale(VAS)],occurrence of CRBD,intraoperative dose of sufentanil,degree of sedation after tracheal catheter withdrawal,mean arterial pressure(MAP),heart rate(HR)were compared between the two groups.Results The VAS scores of observation group after extubation,15 min,30 min,1 h,2 h and 4 h were lower than those of control group(P<0.05).The severity of CRBD in observation group was better than that in control group(P<0.05).The intraoperative dose of sufentanil in the observation group was(0.31±0.17)μg/kg,lower than that in the control group(0.62±0.22)μg/kg(P<0.05),and the score of sedation degree in the observation group was(2.34±0.26)points,lower than that in the control group(5.27±0.36)points(P<0.05).The MAP and HR of the observation group at T1,T2,T3 and T4 were lower than those of the control group(P<0.05).Conclusion Dezocine has obvious preventive effect on urinary CRBD after general anesthesia,can relieve pain,keep vital signs stable,improve sedation effect,reduce the dosage of sufentanil,and has high application value.
万方数据
维普
