Diagnostic Value of Serum Amylase,Creatine Kinase and Inflammatory Factors in the Secondary Infection of Type 2 Diabetes Ketoacidosis
Objective To explore the diagnostic value of serum amylase(AMS),creatine kinase(CK)and serum inflammatory factors in the secondary infection of type 2 diabetes ketoacidosis.Methods A total of 120 patients with type 2 diabetic ketoacidosis treated in Jinnan Branch of Jinjiang Hospital from January 2021 to December 2022 were selected as the research objects.According to whether the patients etiology examination were infected,they were divided into the control group and the observation group.60 patients in the control group were not infected,and 60 patients in the observation group were infected.The levels of AMS,CK and related serum inflammatory factors were compared between the two groups,risk factors were analyzed,and receiver operating characteristic(ROC)curve were drawn for detection of single index and combined index.Results The levels of AMS,CK,procalcitonin(PCT)and interleukin-6(IL-6)in observation group were higher than those in control group(P<0.05).Multiple logistic regression indicated that AMS,CK and PCT were all risk factors for infection in type 2 diabetic ketoacidosis patients(P<0.05).Meanwhile,ROC curve showed that the area under the curve(AUC)of AMS,CK,PCT,IL-6 and combined detection were 0.825,0.884,0.919,0.836 and 0.965,respectively.The accuracy of joint testing is higher than that of single indicator testing(P<0.05).Conclusion The levels of AMS,CK,PCT and IL-6 were increased in patients with type 2 diabetic ketoacidosis infection,and the combined detection of the four indicators has positive significance in improving the sensitivity and accuracy of early diagnosis of type 2 diabetic ketoacidosis with infection.
万方数据
维普
