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CT和MRI评估不可切除性原发性肝癌患者TACE术后疗效的价值

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目的 探讨CT和核磁共振(magnetic resonance imaging,MRI)在不可切除性原发性肝癌(primary liver cancer,HCC)患者经皮肝动脉化疗栓塞术(percutaneous hepatic arterial chemoembolization,TACE)术后疗效,为后期TACE治疗HCC疗效的影像学评价标准的制定提供借鉴。方法 选择2020年1月—2023年1月于惠州市中心人民医院接受TACE介入治疗的 166 例HCC患者作为研究对象。在治疗后 3 个月,所有患者接受CT和MRI扫描检查,以数字减影血管造影(digital subtraction angiography,DSA)检查作为"金标准",分析单独CT检查以及CT联合MRI检查在评价患者术后疗效中的应用价值。结果 入组患者目标病灶最大径线为0。91~14。22 cm,平均(9。19±3。11)cm,经过治疗,病灶缩小程度较为明显,总病灶数由 196 个减少至 172 个,最大径线为 0。65~10。88 cm,平均(7。21±2。12)cm,低于治疗前(P<0。05),检出疾病控制患者132例(79。52%);单独CT检出疾病控制患者112例(67。47%),CT联合MRI检出疾病控制患者 126 例(75。90%);CT联合MRI检查的敏感度和准确率分别为 92。42%和 91。57%,高于单纯CT检查的 81。82%、83。13%(P<0。05),2 种方法特异度比较,差异无统计学意义(P>0。05)。结论 CT联合MRI检查对不可切除性HCC患者TACE介入术后疗效评价效能优于单纯CT检查,其敏感度和准确率较高。
The Value of CT and MRI in Evaluating the Efficacy of TACE Intervention in Patients With Unresectable Primary Liver Cancer
Objective To investigate the efficacy of CT and magnetic resonance imaging(MRI)in patients with unresectable primary liver cancer(HCC)after percutaneous hepatic arterial chemoembolization(TACE).It provides reference for the formulation of imaging evaluation criteria for the efficacy of TACE in the treatment of HCC.Methods A total of 166 patients with primary liver cancer who received TACE interventional therapy in Huizhou Municipal Central Hospital from January 2020 to January 2023 were selected as study subjects.3 months after treatment,all patients received CT and MRI scans,and digital subtraction angiography(DSA)was used as the gold standard.The application value of CT alone and CT combined with MRI in evaluating the postoperative efficacy of patients were analyzed.Results The maximum diameter range of the target lesions in the enrolled patients was 0.91-14.22 cm,with an average of(9.19±3.11)cm.After treatment,the reduction degree of the lesions was obvious,the total number of lesions was reduced from 196 to 172,and the maximum diameter range was 0.65-10.88 cm,with an average of(7.21±2.12)cm,lower than that before treatment(P<0.05),132 cases(79.52%)of disease control patients were detected.Disease control patients were detected in 112 cases(67.47%)by CT alone,126 cases(75.90%)by CT combined with MRI.The sensitivity and accuracy of CT combined with MRI were 92.42%and 91.57%,respectively,higher than 81.82%and 83.13%of CT alone(P<0.05),and there was no significant difference in specificity between the two methods(P>0.05).Conclusion CT combined with MRI is superior to CT alone in evaluating the efficacy of TACE intervention in patients with unresectable primary liver cancer,and its sensitivity and accuracy are higher.

CTmagnetic resonance imagingprimary liver cancerpercutaneous hepatic arterial chemoembolizationefficiencydigital subtraction angiography

吴继雄、林宜圣、张良金、张文俊、陈康胤、石安斌

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汕头大学医学院,广东 汕头 515041

惠州市中心人民医院周围血管介入科,广东 惠州 516001

中信惠州医院有限公司中信惠州医院影像中心,广东 惠州 516006

惠州市中心人民医院放射科,广东 惠州 516001

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CT 核磁共振 原发性肝癌 经皮肝动脉化疗栓塞术 效能 数字减影血管造影

2022年度惠州市医疗卫生领域科技计划项目

2022CZ 010386

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(8)
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