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老年慢性阻塞性肺疾病合并心力衰竭急救治疗效果分析

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目的 探讨老年慢性阻塞性肺疾病合并心力衰竭的急救治疗效果。方法 选择 2021 年 1 月—2023 年 4 月厦门医学院附属第二医院急诊科收治的 70 例慢性阻塞性肺疾病合并心力衰竭患者(≥60 岁),随机分为无创通气组(35 例)和吸氧组(35 例)。2 组患者均立即实施急救,同时吸氧组立即实施面罩吸氧治疗,无创通气组采用无创呼吸机治疗。比较 2 组疗效及预后。结果 无创通气组治疗后血气指标、心率均优于吸氧组,无创通气组左心室射血分数(left ventricular ejection fraction,LVEF)为(52。16±7。24)%,高于吸氧组的(48。25±6。38)%(P<0。05)。无创通气组治疗后血浆氨基末端B型脑利钠肽前体(amino terminal B-type brain natriuretic peptide precursor,NT-proBNP)为(1 682。36±308。74)ng/L,低于吸氧组的(2 056。71±294。63)ng/L(P<0。05),血清肌酸激酶同工酶MB(creatine kinase isoenzyme MB,CK-MB)、血清肌钙蛋白I(troponin I,cTNI)低于吸氧组(P<0。05)。无创通气组治疗后C反应蛋白(C-reactive protein,CRP)、D-二聚体(D-dimer,D-D)、降钙素原(procalcitonin,PCT)、同型半胱氨酸(homocysteine,Hcy)等炎症指标低于吸氧组(P<0。05)。结论 老年慢性阻塞性肺疾病合并心力衰竭患者常规治疗基础上,及时实施无创呼吸机呼吸支持,可有效改善患者血气分析指标,促进心功能恢复,有助于改善患者预后。
Analysis of the Effectiveness of Emergency Treatment for Elderly Chronic Obstructive Pulmonary Disease With Heart Failure
Objective To investigate the emergency treatment effect of chronic obstructive pulmonary disease complicated with heart failure in the elderly.Methods A total of 70 patients(≥60 years old)with chronic obstructive pulmonary disease and heart failure admitted to department of emergency,the Second Affiliated Hospital of Xiamen Medical College from January 2021 to April 2023 were randomly divided into a non-invasive ventilation group(35 cases)and an oxygen inhalation group(35 cases).Both groups of patients were immediately given first aid,while the oxygen inhalation group was immediately treated with mask oxygen therapy,while the non-invasive ventilation group was treated with non-invasive ventilator.The efficacy and prognosis of the two groups were compared.Results After treatment,the blood gas index and heart rate in the non-invasive ventilation group were better than those in the oxygen inhalation group,the left ventricular ejection fraction(LVEF)in non-invasive ventilation group was(52.16±7.24)%,which was higher than that in oxygen inhalation group(48.25±6.38)%(P<0.05).After treatment,the amino terminal B-type brain natriuretic peptide precursor(NT-proBNP)(1 682.36±308.74)ng/L in the non-invasive ventilation group was lower than that in the oxygen inhalation group(2 056.71±294.63)ng/L(P<0.05),and the creatine kinase isoenzyme MB(CK-MB)and troponin I(cTNI)were lower than those in the oxygen inhalation group(P<0.05).The levels of inflammatory indicators such as C-reactive protein(CRP),D-dimer(D-D),procalcitonin(PCT)and homocysteine(PCT)in the non-invasive ventilation group were lower than those in the oxygen inhalation group after treatment(P<0.05).Conclusion On the basis of routine treatment for elderly patients with chronic obstructive pulmonary disease complicated with heart failure,timely implementation of non-invasive ventilator respiratory support can effectively improve the blood gas analysis index of patients,promote the recovery of heart function,and help improve the prognosis of patients.

agednesschronic obstructive pulmonary diseaseheart failurecomplicationsfirst aid effectivenessrespiratory support

卓秀玲、吴发通

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厦门医学院附属第二医院急诊科,福建厦门 361000

邵武市立医院心内科,福建 邵武 354000

老年 慢性阻塞性肺疾病 心力衰竭 并发症 急救效果 呼吸支持

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(8)
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