Application of Multimodal Magnetic Resonance Imaging in Thrombolytic Therapy for Acute Cerebral Infarction
Objective To explore the application value of diffusion-weighted imaging(DWI),diffusion tensor imaging(DTI)and susceptibility weighted imaging(SWI)in thrombolytic therapy for acute cerebral infarction.Methods The data from patients diagnosed with acute cerebral infarction at the Third People's Hospital Affiliated to Fujian University of Chinese Medicine from August 2021 to December 2022 were collected.Those who meet the criteria for intravenous thrombolytic therapy were selected.Further categorize them based on the presence of microbleeds cerebral(CMBs)in the infarct area as shown by SWI.A total of 30 patients with CMBs were categorized into the CMBs group.Correspondingly,select thirty patients without CMBs who visited the hospital during the same period to form a control group for a comparative study.Both groups received rapid intravenous thrombolysis,and SWI was reexamined within 24 hours to detect and count the number of hemorrhagic transformation(HT)cases,and compare whether there was a significant difference between the CMBs group and the non-CMBs group.Results DWI,DTI and SWI could all show acute cerebral infarction lesions,among which DWI had the highest detection rate(100%),followed by DTI(93.3%)and SWI(86.7%),and there were significant differences among them(P＜0.05).SWI could show CMBs,while DWI and DTI could not.After intravenous thrombolysis,SWI was reexamined within 24 hours,and 15 cases(25.0%)had HT,among which 10 cases(33.3%)in the CMBs group and 5 cases(16.7%)in the non-CMBs group had HT,and there was a significant difference between the two groups(P＜0.05).Conclusion Multimodal magnetic resonance imaging can quickly evaluate the hemodynamic status of ischemic brain tissue,providing imaging basis for clinical intravenous thrombolysis,and has important clinical application value.CMBs are an important evaluation factor for thrombolytic therapy,and patients with CMBs have an increased risk of HT during intravenous thrombolysis,so thrombolytic schemes should be carefully selected.
万方数据
维普
