Evaluation of the Efficacy and Safety of Minimally Invasive Surgery and Craniotomy in the Treatment of Cerebral Hemorrhage
Objective To explore the application effect of minimally invasive surgery and craniotomy in patients with cerebral hemorrhage.Methods A total of 80 patients with cerebral hemorrhage in the People's Hospital of Xiangxiang from January 2020 to December 2022 were selected as the study objects.According to random number table method,each group was 40 cases.The control group underwent craniotomy and the observation group underwent minimally invasive surgery.The clinical indexes,brain derived neurotrophic factor(BDNF),matrix metalloproteinase-9(MMP-9),interleukin-1β(IL-1β),thrombospondin2(TSP2)and complication rate of the two groups were compared.Results The operation time and hospital stay in the observation group were shorter than those in the control group,the amount of intraoperative blood loss and surgical incision were shorter than those in the control group,and the differences were statistically significant(P<0.05).After surgery,the BDNF index in the observation group was higher than that in the control group,and the MMP-9 index was lower than that in the control group,the differences were statistically significant(P<0.05).After operation,IL-1β and TSP2 indexes in observation group were lower than those in control group,and the difference was statistically significant(P<0.05).The total incidence of complications in the observation group was 5.00%,lower than that in the control group(20.00%),the difference was statistically significant(P<0.05).Conclusion Minimally invasive surgery can significantly improve BDNF and MMP-9 levels,reduce postoperative complications,and restore neurological function in patients with cerebral hemorrhage during surgery.
万方数据
维普
