Research Status of Early Detection of Hydroxychloroquine Retinopathy
Hydroxychloroquine(HCQ)is increasingly used in the treatment of various autoimmune diseases.However,long-term use of HCQ can lead to irreversible retinal toxicity lesions,and with the progress of detection technology,the incidence is higher than previously recognized,and early detection of HCQ retinopathy can greatly reduce the risk of late progression.At present,the examination methods recommended by the guide include spectral-domain optical coherence tomography(SD-OCT),fundus autofluorescence(FAF),multifocal electroretinogram and automated visual field examination.Recent studies have found that some new retinal imaging technologies may help identify early lesions.The aim is to summarize the examination methods and new imaging technologies currently used in patients with HCQ retinopathy,such as quantitative fundus autofluorescence,microperimetry and retromode imaging,are considered the prospect of using these emerging technologies for early disease detection in the future.