Correlation Between Preoperative Peripheral Platelet/Lymphocyte Ratio and Clinicopathological Features and Prognosis of Patients With Primary Gastric Cancer
Objective To explore the relationship between preoperative peripheral platelet/lymphocyte ratio(PLR)and clinicopathological features of patients with primary gastric cancer,and to analyze the impact on the prognosis of patients.Methods A total of 285 patients with gastric cancer diagnosed and treated in the department of gastrointestinal surgery of Longyan First Hospital from January 2018 to January 2019 were selected.Taking PLR=150 as the baseline,there were 193 patients with low PLR(PLR<150)and 92 patients with high PLR(PLR≥150).The clinicopathological data,1,3 and 5-year overall survival(OS)and disease free survival(DFS)of patients with high and low PLR groups were compared,and Cox risk regression model was used to evaluate the factors affecting the prognosis of patients with gastric cancer.Results The high PLR group had deep tumor infiltration,more lymph node metastasis,late TNM stage and low albumin,which were significantly different from the low PLR group(P<0.05).There were significant differences in OS and DFS in the high PLR group at 1,3 and 5 years(P<0.05).Conclusion preoperative PLR is an independent prognostic factor of DFS in patients with gastric cancer,which can provide basis for clinical treatment.
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