Study on the Therapeutic Effect of Holmium Laser Lithotripsy Through Ureteroscopy for Upper Urinary Tract Stones
Objective To explore and analyze the therapeutic effect of ureteroscopic holmium laser lithotripsy in patients with upper urinary tract stones.Methods A total of 90 patients with upper urinary tract stones who received treatment in the department of urology at People's Hospital Qiandongnan from January 2021 to December 2023 were selected.Among them,45 patients in the control group received percutaneous nephrolithotripsy,while 45 patients in the observation group received treatment with ureteral soft holmium laser lithotripsy.The clinical treatment effects of the two groups of patients were compared.Results The stone clearance rate of patients in the observation group was 97.78%,which was higher than 84.44%in the control group(P<0.05).The recurrence rate of the observation group stones was 0,lower than the control group's 8.89%(P<0.05).Compared with the control group patients,the surgical treatment indicators and pain scores of the observation group patients were relatively good,with a surgical time of(55.53±4.27)minutes,which was shorter than the control group's(76.29±4.84)minutes.The hospitalization time was(6.07±1.32)days,which was shorter than the control group's(9.35±1.50)days.The intraoperative bleeding volume was(17.66±2.25)mL,which was lower than the control group's(46.68±2.27)mL.After surgery,there was a significant improvement in renal function,with neutropil gelatinaseassociated lipocalin(NGAL)levels of(5.48±1.16)μg/L,lower than the control group's(7.32±1.21)μg/L.The serum creatinine(Scr)level was(67.33±7.85)μmol/L,lower than the control group's(75.84±8.97)μ mol/L.The cystatin C(CysC)level was(525.92±81.34)μg/L,lower than the control group's(633.69±70.48)μg/L(P<0.05).The inflammatory data indicators had relatively low values,with a complication rate of 4.44%,lower than the control group's 28.89%(P<0.05).Conclusion The application of ureteroscopic holmium laser lithotripsy in the clinical treatment of upper urinary tract stones has significant results,with relatively high safety and reliability.It can effectively improve the clinical surgical indicators of patients and reduce their pain.At the same time,this treatment plan can effectively improve the renal function of patients,and the postoperative recurrence rate is low,so it can be promoted and applied in clinical practice.
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