艾司氯胺酮用于患儿核磁共振成像检查的安全性及可行性
Safety and Feasibility of Esketamine in Children Used for Magnetic Resonance Imagine
王承海 1林玉芳 1林常森 2赵鲁夕 3姜小燕 1贵浩然 1李琳 1张凯1
作者信息
- 1. 烟台市烟台山医院麻醉科,山东烟台 264008
- 2. 山东中医药大学附属医院麻醉科,山东济南 250014
- 3. 山东中医药大学第一临床医学院外科教研室,山东济南 250014
- 折叠
摘要
目的 探讨艾司氯胺酮在患儿核磁共振成像检查(magnetic resonance imaging,MRI)中的应用价值.方法 选择 2022 年 1 月—2023 年 5 月烟台市烟台山医院和山东中医药大学附属医院收治的 90 例行MRI检查患儿为研究对象,随机分为Ⅰ组(采用丙泊酚)、Ⅱ组(采用右美托咪定)和Ⅲ组(采用艾司氯胺酮),各 30 例.比较 3 组镇静起效时间、MRI检查时间、苏醒时间及检查过程中发生的并发症.结果 Ⅱ组镇静起效时间为(7.73±0.83)min,明显长于Ⅰ组(3.47±0.63)min和Ⅲ组(3.50±0.51)min(P＜0.05).Ⅲ组MRI检查时间明显短于Ⅰ组和Ⅱ组(P＜0.05).Ⅱ组苏醒时间明显长于Ⅰ组和Ⅲ组(P＜0.05).所有患儿均无严重并发症发生.结论 艾司氯胺酮可安全用于患儿MRI,起效快、苏醒快,值得临床进一步研究.
Abstract
Objective To investigate the safety and feasibility of esketamine in children used for magnetic resonance imagine(MRI).Methods A total of 90 pediatric patients undergoing magnetic resonance imaging examination admitted to Yantaishan Hospital,Yantai City and Affiliated Hospital of Shandong University of Traditional Chinese Medicine from January 2022 to May 2023 were collected as the research subjects,and randomly divided into groups Ⅰ(using the propofol),group Ⅱ(using right the microphones)and group Ⅲ(using department of ketamine group),30 cases in each group.The onset time of sedation,MRI examination time,recovery time and complications during the examination were compared among the three groups.Results The onset time of sedation in group Ⅱ was significantly longer than that in group Ⅰ and group Ⅲ(P<0.05).The time of MRI examination in group Ⅲ was significantly shorter than that in group Ⅰ and group Ⅱ(P<0.05).The recovery time of group Ⅱ was significantly longer than that of group Ⅰ and group Ⅲ(P<0.05).No severe complications occurred in all children.Conclusion Esketamine can be safely used in children for MRI,has the advantage of quick onset and rapid awakening,so can be further research in clinic.
关键词
艾司氯胺酮/镇静/患儿/核磁共振/安全性/可行性Key words
esketamine/sedation/children/magnetic resonance/safety/feasibility引用本文复制引用
出版年
2024
NETL
NSTL
万方数据