Analysis on the Medication Law of Traditional Chinese Medicine in the Treatment of Cerebral Infarction Based on Data Mining
Objective To explore the medication patterns and their characteristics of patients with cerebral infarction treated with traditional Chinese medicine(TCM)in the literature in the last 10 years using data mining techniques.Methods By searching the Chinese Biology Medicine disc(CBMdisc),China National Knowledge Internet(CNKI),China Academic Journal Database(Wanfang Data),Chinese Science and Technology Journal Database(Wipo),Chinese Medicine Database(Wanfang Data),and Chinese Journal Database(Wipo)for the period from January 1,2013 to January 1,2023,The stydy found that Chinese medicine was used to treat patients with cerebral infarction.Academic Journal Database(Wanfang Data),Chinese Science and Technology Journal Database(Wipo.com)relevant literature on Chinese medicine(including integrated Chinese and Western medicine)for the treatment of cerebral infarction.After completing the screening and establishing the database,frequency statistics,cluster analysis,association rule analysis and other methods were applied on the Chinese Medicine Inheritance Aid Platform(V3.0)to count the frequency of drug use,the distribution of flavors and attributes,and to analyze the pattern of drug compounding and the effect of association and clustering.Results A total of 143 articles were included,and 161 formulas with 222 flavors of Chinese medicines were compiled;among the four qi,warmth(41.51%),cold(27.55%),and flatness(25.89%)were predominant;among the five flavors,bitterness(34.17%),sweetness(28.82%),and pungency(24.45%)were predominant;and the attributed meridians,liver(26.68%),heart(17.96%),and spleen(16.14%)were predominant.16.14%)meridians were predominant;a total of 13 traditional Chinese medicines with drug frequency≥35 times were predominantly blood-activating and blood-stasis-removing drugs;there were 18 groups of drug combinations with frequency≥45 times;and the collated 222 traditional Chinese medicines could be classified into 3 clusters.Conclusion The therapeutic drugs for cerebral infarction were mostly warm,cold and flat,and attributed to the heart and liver meridians,and the treatment method was based on activating blood circulation and removing blood stasis,tonifying the liver and kidney,and calming the liver and extinguishing wind,which could provide some reference for clinical treatment.
cerebral infarctiondata miningmedication lawtraditional Chinese medicineliterature researchapply
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