The Value of Lung Ultrasound Scores at 1 Week Postnatal in Predicting Bronchopulmonary Dysplasia in Preterm Infants at 32 Weeks
Objective To investigate the role of lung ultrasound score in the prediction of bronchopulmonary dysplasia(BPD)in preterm infants within 32 weeks after birth.Methods A total of 121 preterm infants with gestational age<32 weeks were enrolled in the department of neonatology,Zhangzhou Affiliated Hospital of Fujian Medical University from October 2019 to August 2020,including 69 infants in the non-BPD group and 52 infants in the BPD group.All preterm infants underwent lung ultrasonography and scoring at 1 week after birth and maternal age,complications(including gestational hypertension,gestational diabetes,placental abruption,placenta previa)and general conditions of preterm infants(gestational age,sex,body weight,mode of delivery,invasive ventilation,fluid intake and output within one week after birth,etc.)and early complications[early-onset sepsis,patent ductus arteriosus(PDA),neonatal respiratory distress syndrome(NRDS),asphyxia,etc.],the differences of the above parameters between the two groups of preterm infants were compared,and the statistically different parameters were analyzed by binary logistic regression.Finally,the receiver operating characteristic(ROC)curve was drawn to analyze its diagnostic performance.Results Parameters with statistical differences in univariate analysis(invasive ventilation,gestational age,mode of delivery,body weight,NRDS,PDA,asphyxia,fluid intake and outflow within one week after birth,and pulmonary ultrasound score within one week after birth)were displayed by binary logistic regression:fetal age(OR=0.497,95%CI 0.280-0.882,P<0.05)and first week LUS score(OR=1.429,95%CI 1.188-1.720,P<0.001)were independent risk factors for the occurrence of BPD.ROC curve was made for ultrasonic scores,and the analysis showed that pulmonary ultrasound scores were significant factors in the occurrence of BPD,with an AUC of 0.827(95%CI 0.752-0.90)and the optimal cutoffvalue of 9.5,with sensitivity of 86.5%and specificity of 71.0%.Conclusion LUS score and gestational age at 1 week after birth were independent risk factors for BPD,and LUS score was significantly correlated with BPD and could be used as a predictor of BPD.
万方数据
维普
