首页|股骨近端防旋髓内钉联合解剖型锁定钢板治疗老年不稳定型股骨粗隆间骨折的临床效果

股骨近端防旋髓内钉联合解剖型锁定钢板治疗老年不稳定型股骨粗隆间骨折的临床效果

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对比单用股骨近端防旋髓内钉与联合解剖型锁定钢板治疗老年不稳定型股骨粗隆间骨折的效果。方法 研究对象均为 2021 年 1 月—2022 年 12 月莆田九十五医院收治的 62 例老年不稳定型股骨粗隆间骨折患者,随机分为观察组和对照组,各 31 例。观察组采用股骨近端防旋髓内钉联合解剖型锁定钢板治疗,对照组单用股骨近端防旋髓内钉治疗。比较 2 组围手术期指标、炎症因子水平、骨代谢指标水平、髋关节功能、并发症发生情况。结果 观察组手术时间[(81。45±11。63)min]长于对照组[(63。71±9。24)min],术中出血量[(165。41±22。74)mL]多于对照组[(127。82±24。32)mL],负重时间[(11。93±2。76)d]、骨折愈合时间[(10。42±2。07)周]短于对照组[(15。38±3。59)d、(13。92±2。43)周],差异有统计学意义(t=6。650、6。286、4。242、6。105,P<0。001)。手术后 1 个月,观察组白细胞介素-1 水平(39。07±5。37)pg/mL,白细胞介素-6水 平(32。14±2。72)pg/mL,肿 瘤 坏 死 因 子-α水 平(30。97±2。16)pg/mL,均低于对照组[(48。14±6。23)pg/mL、(43。66±3。25)pg/mL、(37。32±2。87)pg/mL],差异有统计学意义(t=6。139、15。135、9。843,P<0。001)。手术后 1 个月,观察组Ⅰ型胶原羧基末端肽水平[(472。91±25。24)ng/L]低于对照组[(521。46±27。63)ng/L],观察组Ⅰ型前胶原氨基端前肽水平[(84。59±9。20)ng/mL]高于对照组[(73。61±8。64)ng/mL],差异有统计学意义(t=7。223、4。844,P<0。001)。观察组髋关节优良率(93。55%)高于对照组(74。19%),差异有统计学意义(χ2=4。292,P=0。038)。观察组并发症发生率(3。23%)低于对照组(19。35%),差异有统计学意义(χ2=4。026,P=0。045)。结论 股骨近端防旋髓内钉联合股骨近端解剖型锁定钢板治疗老年不稳定型股骨粗隆间骨折患者的效果较好,可以缓解炎症反应,促进骨质修复,抑制骨吸收,提高髋关节功能,降低并发症发生率。
Clinical Effect of Proximal Femoral Antirotation Intramedullary Nail Combined With Anatomic Locking Plate in the Treatment of Unstable Intertrochanteric Femoral Fractures in the Elderly
Objective To explore the clinical effect of proximal femoral antirotation intramedullary nail combined with anatomic locking plate in the treatment of unstable intertrochanteric femoral fractures in the elderly.Methods Sixty-two elderly patients with unstable intertrochanteric fracture of femur in Putian 95 Hospital from January 2021 to December 2022 were selected as the study objects,and randomly divided into observation group and control group,with 31 cases in each group.The observation group was treated with proximal femoral antirotation intramedullary nailing combined with anatomic locking plate,while the control group was treated with proximal femoral antirotation intramedullary nailing.Compared the perioperative indicators,serum inflammatory factors and bone metabolism levels,hip joint function,and incidence of complications between two groups.Results The operation time[(81.45±11.63)min]in the observation group was longer than that in the control group[(63.71±9.24)min],and the amount of intraoperative blood loss[(165.41±22.74)mL]was longer than that in the control group[(127.82±24.32)mL],weight bearing time[(11.93±2.76)d]and fracture healing time[(10.42±2.07)weeks]were shorter than control group[(15.38±3.59)d,(13.92±2.43)weeks],the differences were statistically significant(t=6.650,6.286,4.242,6.105,P<0.001).One month after the surgery,the levels of interleukin-1,interleukin-6,tumor necrosis factor-α[(39.07±5.37)pg/mL,(32.14±2.72)pg/mL,(30.97±2.16)pg/mL]in observation group were lower than those in control group[(48.14±6.23)pg/mL,(43.66±3.25)p g/m L,(37.32±2.87)pg/mL],the differences were statistically significant(t=6.139,15.135,9.843,P<0.001).One month after operation,the level of carboxyl terminal peptide of typeⅠ collagen in the observation group[(472.91±25.24)ng/L]was lower than that in the control group[(521.46±27.63)ng/L],the level of amino terminal propeptide of typeⅠprocollagen in the observation group[(84.59±9.20)ng/mL]was higher than that in the control group[(73.61±8.64)ng/mL],and the differences were statistically significant(t=7.223,4.844,P<0.001).The excellent rate of hip joint in observation group(93.55%)was higher than that in control group(74.19%),and the difference was statistically significant(χ2=4.292,P=0.038).The complication rate of the observation group(3.23%)was lower than that of the control group(19.35%),and the difference was statistically significant(χ2=4.026,P=0.045).Conclusion Proximal femoral antirotation intramedullary nail combined with proximal femoral anatomic locking plate is effective in the treatment of elderly patients with unstable intertrochanteric fractures,which can alleviate inflammatory response,promote bone repair,inhibit bone resorption,improve hip function and reduce the incidence of complications.

proximal femoral antirotation intramedullary nailintertrochanteric fracture of femuranatomic locking plate for proximal femurcomplicationsinflammatory factorsbone metabolism

林智星、林正龙

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莆田九十五医院骨科,福建 莆田 351100

股骨近端防旋髓内钉 股骨粗隆间骨折 股骨近端解剖型锁定钢板 并发症 炎症因子 骨代谢

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(13)