Analysis of Genotyping Results of HPV Infection in Rural Women in Zhangzhou From 2021 to 2022
Objective The detection results of human papilloma virus(HPV)in rural women in Zhangzhou from 2021 to 2022 were analyzed,and the genotyping of HPV infection in rural women in Zhangzhou was discussed.Methods In this study,a total of 76 505 rural women in Zhangzhou were tested for HPV from 2021 to 2022.The testing type was HPV21 genotype,and cervical exfoliated cells were tested to analyze the HPV infection status of rural women in the area.Single infection,double infection,triple infection,and multiple infection,as well as the infection status of various subtypes of HPV,were also analyzed.Results A total of 4 376 positive cases(9.55%)were detected in 45 838 subjects tested in 2021,and 3 886 positive cases(12.67%)were detected in 30 667 subjects tested in 2022.There was statistical significance in the positive infection rate between 2021 and 2022(P<0.05).There were 6 515 cases of single infection(8.52%),1 284 cases of double infection(1.68%),332 cases of triple infection(0.43%),and 131 cases of multiple infection(0.17%).Among them,HPV gene infection subtypes mainly include HPV52,HPV58,HPV16,HPV53,HPV39,HPV CP8304,etc.,among the high-risk HPV gene subtypes in 2021 and 2022,accounting for a high proportion in 2 years,among which high-risk HPV gene subtypes in 2021 and 2022,HPV52(1.87%,2.27%),HPV16(1.02%,1.12%),HPV58(0.82%,1.36%),HPV39(0.91%,1.08%),HPV51(0.46%,1.05%).There was no statistical significance in the distribution of middle-risk HPV genotypes in 2021 compared with 2022(P>0.05).There was significant difference between the genotypes of low-risk HPV in 2021 and 2022(P<0.05),but the infection rate of HPV CP8304 was higher(0.67%and 1.32%,respectively).The HPV infection subtypes of rural women in Zhangzhou in the past 2 years were summarized,and the infection rates of high-risk HPV gene subtypes were the highest,reaching 81.10%and 76.94%,but the difference was statistically significant(P<0.05).Conclusion HPV testing of rural women in Zhangzhou from 2021 to 2022 found that rural women in this region have a high HPV infection rate,and the HPV genotypes infected are more,and most of them are single infections,among which the infection rates of HPV16,HPV52,HPV58 and other genotypes are high,which should be paid attention to.Strengthen the awareness of cervical disease screening for HPV infected people,conduct regular review,and effectively prevent cervical cancer.
Zhangzhourural womencervical cancer screeningHPV testingprevention of diseaseanalysis of results
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