Prognostic Value of Cerebral CT Perfusion Imaging in the Treatment of Intracranial Large Vessel Occlusion in Acute Cerebral Infarction
Objective To investigate the predictive value of cerebral CT perfusion imaging parameters in patients with acute cerebral infarction with intracranial large vessel occlusion after treatment.Methods A total of 90 patients with intracranial large vessel occlusion with acute cerebral infarction admitted to Liaocheng People's Hospital from September 2020 to September 2022 were selected as the study objects.After treatment,the patients were divided into good prognosis group(62 cases)and bad prognosis group(28 cases).All performed brain CT perfusion imaging parameters,compared brain CT perfusion imaging parameters and drew receiver operating characteristic(ROC)curves.Results In patients with acute cerebral infarction,the cerebral blood volume(CBV)and cerebral blood flow(CBF)of cerebral infarction area were(3.01±0.82)mL/(min·100 g)and(43.57±10.35)mL/(min·100 g)respectively,which was lower than(5.69±1.23)mL/(min·100 g)and(85.36±18.24)mL/(min·100 g)of the healthy side of brain,and the difference was statistically significant(P<0.05).Mean transit time(MTT)and time to peak(TTP)in cerebral infarction area were(6.12±1.34)s and(18.62±2.21)s,which were longer than(2.59±1.32)s and(7.24±1.32)s in the healthy side of brain,and the difference was statistically significant(P<0.05).In the bad prognosis group,the CBV was(2.35±0.24)mL/(min·100 g)and the CBF was(21.35±4.52)mL/(min·100 g),which was lower than(3.12±0.21)mL/(min·100 g)and(47.26±5.26)mL/(min·100 g)in the good prognosis group,and the difference was statistically significant(P<0.05).MTT and TTP of thebad prognosis group were(6.53±2.41)s and(24.53±4.62)s,which were longer than(4.13±1.52)s and(9.34±1.82)s of the good prognosis group,and the difference was statistically significant(P<0.05).In ROC curve,the diagnostic sensitivity of CBV parameter was the highest(96.40%),and the specificity of MTT parameter was the highest(77.40%).Conclusion Brain CT perfusion imaging index can be used as an important index to assess the prognosis of patients with cerebral infarction,among which the CBV index has high sensitivity and specificity for assessing the prognosis of patients with cerebral infarction,and the combination of other imaging indexes is of great significance for assessing the prognosis of patients with cerebral infarction.The results of this study provide a reference for the development of prognostic criteria for acute cerebral infarction with intracranial large vessel occlusion.
cerebral CTperfusion imaging parametersacute cerebral infarctionintracranial large vessel occlusionprognosispredictive value
万方数据
维普
