Analysis of the Effect of 0.5%Ropivacaine Scalp Nerve Block in Craniotomy Surgery
Objective To study the effect of scalp nerve block with 0.5%ropivacaine on postoperative inflammatory factors,hemodynamics and analgesic effect in patients undergoing craniotomy.Methods The clinical data of 86 patients who underwent craniotomy in Yancheng NO.1 People's Hospital from January 2020 to January 2023 were retrospectively analyzed..Patients were grouped according to different narcotic,namely,43 cases in the reference group and 43 cases in the test group.1%lidocaine scalp nerve block was performed in the reference group,and scalp nerve block with 0.5%ropivacaine was carried out in the test group.Inflammatory factors,hemodynamics,analgesic effects and adverse events of the two groups of patients at different times should be compared.Results The levels of C-reactive protein(CRP)and interleukin-6(IL-6)in 2 groups at 6,24 and 48 h after operation were higher than those before operation,and the levels of interleuin 10(IL-10)were lower than those before operation,the difference was statistically significant(P<0.05).The levels of CRP and IL-6 in test groups were lower than those in reference group at 6,24,48 and 72 h after operation,and the levels of IL-10 were higher than those in reference group,the differences were statistically significant(P<0.05).The heart rate(HR)and mean arterial pressure(MAP)of the 2 groups immediately after skin resection(T1),at craniotomy(T2)and suture(T3)were higher than those before induction(T0),and the differences were statistically significant(P<0.05).HR and MAP of T1,T2 and T3 in test groups were lower than those in reference group,and the differences were statistically significant(P<0.05).The pain scores of test groups at 2,4,8 and 12 h after operation were lower than those of the reference group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in test group was 6.98%,lower than 23.26%in reference group,the difference was statistically significant(P<0.05).Conclusion Cephalic nerve block with 0.5%ropivacaine in craniotomy can effectively reduce postoperative inflammatory reaction,improve hemodynamics,relieve pain,and reduce the incidence of adverse reactions.
万方数据
维普
