Observation on the Effect of Jiangu Pills in the Treatment of Osteoporotic Peripheral Pain
Objective To Explore the therapeutic effect of Jiangu Pills on osteoporotic peripheral pain and its impact on bone metabolism.Methods A total of 92 patients with thoracolumbra and lumbar compression fractures accompanied by osteoporotic peripheral pain admitted to Affiliated Hospital of Nanjing University of Chinese Medicine from January 2022 to June 2023 were selected as the study objects.They were randomly divided into a control group and an observation group,with 46 patients in each group.The control group received routine treatment,while the observation group received"routine+Jiangu Pills"treatment.The improvement of pain,TCM syndrome score,inflammation level,bone metabolism and drug safety were compared between the two groups.Results The pain of both groups was alleviated after treatment,and the pain score of the observation group was lower than that of the control group 1 and 2 months after treatment(P<0.05).The traditional Chinese medicine syndrome scores(lower back pain,lower limb pain,lumbar spine soreness,and walking weakness)of the observation group patients after treatment were lower than those of the control group(P<0.05).After treatment,the performance of interleukin-6(IL-6),C-reactive protein(CRP),tumor necrosis factor-α(TNF-α)in the observation group was(4.41±1.13)pg/mL,(5.05±1.12)ng/mL and(6.11±2.42)ng/mL,respectively,which was lower than(6.05±1.08)pg/mL,(7.96±1.51)ng/mL and(8.82±2.71)ng/mL of control group(P<0.05).After treatment,bone gla protein(BGP)in observation group was(4.19±0.37)μg/L,which was higher than(3.45±0.26)μg/L in control group.Alkaline phosphatase(ALP)was(82.91±6.28)U/L,lower than(105.37±8.72)U/L in the control group(P<0.05).No adverse reactions were observed in 2 groups during medication,and the medication was safe and reliable.Conclusion In the treatment of osteoporotic peripheral pain,Jiangu Pills can effectively reduce the degree of pain,lower inflammatory levels,and improve traditional Chinese medicine syndromes.It has a significant comprehensive effect,reflecting the clinical reference of the Expert Consensus on the Prevention and Treatment of Primary Osteoporosis with Traditional Chinese Medicine.
osteoporosispain all over the bodyJiangu Pillsbone metabolismbone densitycurative effect
万方数据
维普
