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神经外科导尿管相关性尿路感染的高危因素及预防策略

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目的 探讨神经外科导尿管相关性尿路感染(catheter-associated urinary tract infection,CAUTI)发生的高危因素及预防干预策略。方法 选择 2018 年 1 月—2023 年 10 月广西医科大学第一附属医院神经外科收治的 218 例留置导尿管患者作为研究对象。统计不同临床特征患者CAUTI的发生率,进行多因素logistic回归分析,并提出相应的预防干预策略。结果 218 例神经外科导尿管患者中,发生CAUTI的患者为 35 例,发生率为 16。06%。其中 35 例CAUTI患者检出病原菌 103 株,大肠埃希菌 82 株(79。61%),肺炎克雷伯菌 19 株(18。45%),金黄葡萄球菌 2 株(1。94%)。不同性别、年龄、是否意识障碍、尿道口清洗频率、导尿管留置时间、导尿管更换时间、患者24 h尿量、是否有既往大型手术史、合并不同个数其他疾病的尿路感染率比较,差异有统计学意义(P<0。05)。多因素logistic回归分析结果显示,女性、年龄>65~75 岁、患者意识障碍、尿道口清洗频率为 1 次/d、导尿管留置时间>10 d、导尿管更换时间>15 d是尿路感染率高的危险因素(P<0。05)。结论 神经外科留置导尿管患者CAUTI发生率较高,临床需重点观察女性、年龄>65~75 岁、存在意识障碍、尿道口清洗频率1次/d、导尿管留置时间>10 d、导尿管更换时间>15 d的患者,制定针对性的预防措施,降低CAUTI发生风险。
Risk Factors and Prevention Strategies of Neurosurgical Catheter-Associated Urinary Tract Infection
Objective To explore the risk factors of neurosurgical catheter-associated urinary tract infection(CAUTI)and the prevention and intervention strategies.Methods A total of 218 patients with indwelling catheter admitted to the department of neurosurgery,the First Affiliated Hospital of Guangxi Medical University from January 2018 to October 2023 were selected as the study objects.The incidence of CAUTI in patients with different clinical characteristics was analyzed.Multivariate logistic regression analysis was carried out and corresponding preventive intervention strategies were proposed.Results Among 218 patients with neurosurgical catheter,CAUTI occurred in 35 patients(16.06%).Among the 35 CAUTI patients,103 strains of pathogenic bacteria were detected,82 strains of Escherichia coli(79.61%),19 strains of Klebsiella pneumoniae(18.45%)and 2 strains of Staphylococcus aureus(1.94%).There were statistically significant differences in urinary tract infection rates among different gender,age,consciousness disorder,frequency of urethral orifice cleaning,catheter retention time,catheter replacement time,24 h urine volume,history of previous major surgery,and different numbers of other diseases(P<0.05).The results of multivariate logistic regression analysis showed that gender was female,age>65 to 75 years old,patients with consciousness disorder,frequency of urethral opening cleaning once/d,catheter retention time>10 d,catheter replacement time>15 d were the risk factors for high urinary tract infection(P<0.05).Conclusion The incidence of CAUTI is high in patients with indurating catheter in neurosurgery.It is necessary to focus on the clinical observation of female patients,aged>65 to 75 years,patients with consciousness disturbance,urethral opening cleaning frequency once/d,catheter induration time>10 d,catheter replacement time>15 d,and formulate targeted preventive measures to reduce the risk of CAUTI occurrence.

neurosurgicalcatheterurinary tract infectionpathogenic bacteriahigh risk factorsintervention strategy

黎秀婵、黄晓菲、王丽如、方建冰、麦惠

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广西医科大学第一附属医院神经外科,广西南宁 530021

神经外科 导尿管 尿路感染 病原菌 高危因素 干预策略

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(14)