首页|结核感染T细胞斑点试验诊断女性生殖器结核的价值

结核感染T细胞斑点试验诊断女性生殖器结核的价值

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目的 探讨结核抗体检测(tuberculosis antibody testing,TB-Ab)与结核感染T细胞斑点试验(T-cell spot of tuberculosis,T-SPOT。TB)诊断女性生殖器结核(female genital tuberculosis,FGT)的临床价值。方法 选取2021年1月—2023 年12 月济宁市公共卫生医疗中心收治的82 例临床初诊怀疑FGT的患者为研究对象。分别采用TB-Ab和T-SPOT。TB对患者进行检查,统计阳性检出率。以子宫内膜病理检查结果为"金标准",评价 2 项诊断技术对FGT的诊断效能。结果 基于"金标准",TB-Ab诊断FGT的敏感度、特异度与准确率分别为 69。10%、72。73%、69。51%,T-SPOT。TB诊断FGT的敏感度、特异度与准确率分别为 91。55%、90。91%、91。46%,TB-Ab联合T-SPOT。TB诊断FGT的敏感度、特异度与准确率分别为 94。37%、90。91%、93。90%。T-SPOT。TB诊断FGT的敏感度与准确率均高于TB-Ab,差异有统计学意义(P<0。05);TB-Ab联合T-SPOT。TB诊断FGT的敏感度与准确率高于TB-Ab单一诊断,差异有统计学意义(P<0。05),但与T-SPOT。TB诊断比较,差异无统计学意义(P>0。05)。结论 T-SPOT。TB对FGT的诊断效能高于TB-Ab,更具临床应用价值。
The Value of T-Cell Spot of Tuberculosis in Diagnosing Female Genital Tuberculosis Caused by Tuberculosis Infection
Objective To explore the clinical value of tuberculosis antibody detection(TB-Ab)and T-cell spot of tuberculosis(T-SPOT.TB)in diagnosing female genital tuberculosis(FGT).Methods A total of 82 patients with suspected FGT at the initial clinical diagnosis admitted to Jining Public Health Medical Center from January 2021 to December 2023 were selected as the study subjects.TB-Ab and T-SPOT.TB respectively conducts examinations on patients and counts the positive detection rate were used.Using endometrial pathological examination results as the"gold standard",the diagnostic efficacy of two diagnostic techniques for FGT were evaluated.Results Based on the"gold standard",the sensitivity,specificity,and accuracy of TB-Ab in diagnosing FGT were 69.10%,72.73%,and 69.51%,respectively,the sensitivity,specificity,and accuracy of T-SPOT.TB in diagnosing FGT were 91.55%,90.91%,and 91.46%,respectively,TB-Ab combined with T-SPOT.TB The sensitivity,specificity,and accuracy of TB diagnosis for FGT are 94.37%,90.91%,and 93.90%,respectively.The sensitivity and accuracy of T-SPOT.TB in diagnosing FGT are higher than TB Ab,and the difference is statistically significant(P<0.05).TB Ab combined with T-SPOT.TB The sensitivity and accuracy of diagnosis for FGT are higher than those of TB-Ab single diagnosis,and the difference is statistically significant(P<0.05),but compared to T-SPOT.TB There was no statistically significant difference in TB diagnosis comparison(P>0.05).Conclusion T-SPOT.TB The diagnostic efficacy for FGT is higher than that of TB-Ab,and it has more clinical application value.

womengenitaliatuberculosistuberculosis antibody testingtuberculosis infection T cell spot testdiagnostic efficacy

王翠荣、孙林林

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济宁市公共卫生医疗中心妇产科,山东济宁 272031

济宁市公共卫生医疗中心呼吸内科,山东济宁 272031

女性 生殖器 结核 结核抗体检测 结核感染T细胞斑点试验 诊断效能

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(15)