The Effect of Repeated Transcranial Magnetic Stimulation on Post-Stroke Aphasia With Depression Patients
Objective To analyze the effect of repeated transskull magnetic stimulation on quality of life and depression in patients with aphasia after stroke.Methods A total of 90 patients with aphasia complicated with depression after stroke were enrolled in the First Affiliated Hospital of Xiamen University From April 2021 to March 2022,they were randomly divided into control group and study group.The study group was given repeated transcranial magnetic stimulation intervention and antidepressant treatment according to the doctor's advice,while the control group was given routine rehabilitation and basic drug therapy.The two groups were treated for 1 month.The ADL of all patients before and after the intervention was evaluated by modified Barthel index(MBI).stroke aphasic depression questionnaire hospital version(SADQ-H)and mismatch negative(MMN)were used to analyze the depression status before and after intervention.Results Before the intervention,there was no significant difference in MBI score and SADQ-H score between the two groups(P>0.05).After the intervention,compared with the MBI score of the control group(60.3±4.4)points,the MBI score of the study group was higher(72.7±6.7)points,while the SADQ-H score of the control group was(31.3±6.4)points and the SADQ-H score of the study group was lower(26.6±5.7)points(P<0.05).There was no significant difference in MMN amplitude and MMN latency between the two groups before intervention(P>0.05).After the intervention,compared with the control group,the amplitude of MMN in the study group increased significantly,while the latency of MMN decreased significantly,with statistical significance(P<0.05).Conclusion Repetitive high frequency transcranial magnetic stimulation can improve the quality of life of patients with post-stroke aphasia complicated with depression.
clinical observationADLepressive stateaphasia after strokerepetitive transcranial magnetic stimulationMBIMMN
NETL
NSTL
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