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腹腔镜辅助胃癌根治术在胃癌治疗中的应用价值

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目的 分析腹腔镜辅助胃癌根治术在胃癌治疗中的应用价值。方法 选取宁夏医科大学总医院胃肠外科2021年10月—2023 年 10 月胃癌患者 110 例,按照随机数字表法分为 2 组,各 55 例。对照组采取开腹胃癌根治术,观察组采取腹腔镜辅助胃癌根治术。比较 2 组各指标差异。结果 观察组手术时间[(212。4±20。6)min]长于对照组[(176。4±30。6)min],术中出血量、术后并发症发生率[(250。3±23。6)mL、1。8%]低于对照组[(330。6±35。6)mL、14。6%],切口长度、下床活动时间、住院时间[(3。5±0。6)cm、(36。6±4。2)h、(8。6±2。2)d]短于对照组[(8。8±1。2)cm、(45。6±5。8)h、(11。4±3。6)d],差异均有统计学意义(P<0。05)。手术前,2 组CRP、IL-6相比,差异无统计学意义(P>0。05);手术后,观察组CRP、IL-6[(26。5±5。2)mg/L、(65。3±5。3)pg/mL]低于对照组[(58。5±8。6)mg/L、(78。5±10。6)pg/mL],差异均有统计学意义(P<0。05)。结论 腹腔镜辅助胃癌根治术的疗效与安全性高,可减轻手术引起的机体损伤,促使患者早期出院。
Application Value of Laparoscopic Assisted Radical Gastrectomy in the Treatment of Gastric Cancer
Objective To analyze the application value of laparoscopic assisted radical gastrectomy in the treatment of gastric cancer.Methods A total of 110 patients with gastric cancer in the department of gastrointestinal surgery,General Hospital of Ningxia Medical University from October 2021 to October 2023 were selected and divided into two groups by systematic random sampling,with 55 cases in each group.The control group underwent laparotomy and the observation group underwent laparoscopically assisted radical gastrectomy.The differences in various indicators between two groups were compared.Results The observation group had a longer surgical time[(212.4±20.6)min]than the control group[(176.4±30.6)min],intraoperative blood loss and incidence of postoperative complications[(250.3±23.6)mL,1.8%]were lower compared to the control group[(330.6±35.6)mL,14.6%].The incision length,ambulation time and hospitalization time[(3.5±0.6)cm,(36.6±4.2)h,(8.6±2.2)d]were shorter than those of the control group[(8.8±1.2)cm,(45.6±5.8)h,(11.4±3.6)d],the differences were statistically significant(P<0.05).Before surgery,there was no statistically significant difference in CRP and IL-6 levels between the two groups(P>0.05).After surgery,the CRP and IL-6[(26.5±5.2)mg/L,(65.3±5.3)pg/mL]in the observation group were lower than those in the control group[(58.5±8.6)mg/L,(78.5±10.6)pg/mL],the differences were statistically significant(P<0.05).Conclusion Laparoscopic assisted radical gastrectomy has high efficacy and safety,can reduce the body injury caused by surgery,and promote the early discharge of patients.

laparoscopic assisted radical gastrectomygastric cancerserum indexprognosisinflammatory responserecurrence rate

徐祖培、张曹、李如意

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宁夏医科大学第一临床医学院,宁夏 银川 750004

宁夏医科大学总医院胃肠外科,宁夏 银川 750004

腹腔镜辅助胃癌根治术 胃癌 血清指标 预后 炎症反应 复发率

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(15)