Clinical Value Analysis of Urine Routine Testing in Patients With Hyperthyroidism
Objective To explore the value of urine routine testing in the clinical diagnosis and treatment of hyperthyroidism(hyperthyroidism).Methods A total of 200 hyperthyroidism patients diagnosed and treated in Zhangzhou Municipal Hospital of Fujian Province from January 2021 to June 2023 were selected as the study group,and 100 healthy volunteers who underwent physical examination during the same period were selected as the control group.Urine routine detection and thyroid hormone determination were performed.Urinary pH value,urinary protein,urinary ketone body,urinary bilirubin,urinary sugar levels and serum free triiodothyronine(FT3),free tetraiodothyronine(FT4)and thyroid stimulating hormone(TSH)levels of the two groups were compared,and the correlation between the two groups was analyzed.Results The urine pH of the study group was(5.89±1.04),lower than(6.55±0.42)of the control group.The levels of urinary density,urinary protein,urinary ketone body,urinary bilirubin and urinary sugar were(1.12±0.08)g/cm3,(175.45±22.52)mg/L,(0.74±0.12)mmol/L,(7.12±1.06)mg/L,(2.81±0.45)mmol/L,respectively,which were higher than(1.01±0.02)g/cm3,(146.25±20.14)mg/L,(0.41±0.20)mmol/L,(4.41±1.05)mg/L,(1.72±0.33)mmol/L of the control group,the difference was statistically significant(P<0.05).Serum FT3 and FT4 in the study group were(21.22±10.42)pmol/L and(49.74±18.62)pmol/L,respectively,which were higher t h a n(4.83±0.93)p m o l/L and(13.25±1.81)pmol/L in the control group,and TSH was(0.21±0.03)μIU/mL,which was lower than(1.62±0.15)μIU/mL of control group,the difference was statistically significant(P<0.05).Pearson correlation analysis showed that urine density,urinary protein,urinary ketone body,urinary bilirubin and urinary sugar of patients with hyperthyroidism were positively correlated with FT3 and FT4(P<0.05),and negatively correlated with TSH(P<0.05).Conclusion Urinary routine indicators in patients with hyperthyroidism show significant changes compared to healthy individuals and are correlated with thyroid hormone levels.They can serve as potential auxiliary indicators for the diagnosis and treatment of hyperthyroidism.
万方数据
维普
