Observation on the Therapeutic Effect of Percutaneous Nephrolithotomy for Upper Urinary Tract Stones Combined With Severe Hydronephrosis
Objective To explore the clinical efficacy of minimally invasive percutaneous nephrolithotomy in the treatment of upper urinary tract stones with severe hydronephrosis,and analyzing the clinical value of this treatment plan.Methods From January 2022 to December 2023,a total of 112 patients at Qiandongnan Prefecture People's Hospital were selected and treated primarily with surgery.All patients had clinically confirmed upper urinary tract stones and significant hydronephrosis.Using randomization blinding,double-blind method,they were divided into two groups of 56 each.The control group received conventional percutaneous nephrolithotomy,while the observation group underwent minimally invasive percutaneous nephrolithotomy.The study observed stone clearance rates,recurrence rates,surgical parameters,inflammation markers,and complication rates in both groups of patients with upper urinary tract stones and severe hydronephrosis.Results The stone clearance rate in the observation group was 96.43%,which higher than 83.93%of the control group(P<0.05).The observation group had a stone recurrence rate was 3.57%,which was lower than 16.07%of the control group(P<0.05).The observation group underwent surgery for an average was(41.24±3.60)minutes,significantly less than(70.95±4.96)minutes of the control group(P<0.05).The observation group spent was(10.21±1.36)days in the hospital,which was shorter than(18.59±2.45)days of control group(P<0.05).The recovery time of gastrointestinal function in the observation group was(20.27±1.65)hours,which was earlier than that(38.63±3.68)hours of the control group(P<0.05).The intraoperative blood loss in the observation group was(91.20±11.59)mL,less than(119.62±19.64)mL of the control group(P<0.05).The serum inflammatory factors in the observation group were significantly lower than those in the control group,and the postoperative complication rate was 10.71%,which was lower than 26.79%of the control group(P<0.05).Conclusion For patients with severe hydronephrosis and upper urinary tract stones,the application of minimally invasive percutaneous nephrolithotomy is more effective in treating the condition,which can effectively improve the patient's surgical indicators.The stone clearance rate of the patient is high,and the postoperative recovery is considerable,with significant clinical application value.
万方数据
维普
