Application Value of Combined Detection of Diabetic Autoimmune Antibodies in the Classification of Diabetes Mellitus
Objective To analyze the application value of combined detection of diabetic autoimmune antibodies in diabetes classification.Methods A total of 64 diabetic patients diagnosed and treated in Dongguan Hospital of Traditional Chinese Medicine from January 2021 to November 2023 were included in the study group,incluing 22 patients with type 1 diabetes mellitus(T1DM),42 patients with type 2 diabetes mellitus(T2DM)and 61 healthy patients were included in the control group during the same period.Both two groups were tested for diabetes classification antibodies.The difference of the antibody between the two group and its value in diabetes classification were compered.Results The positive rates of serum glutamic acid decarboxylase antibody(GADA),islet cell antibody(ICA),insulin autoantibodies(IAA)and their combined detection in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The positive rates of ICA,IAA and the combined test of T1DM patients were higher than those of T2DM patients,and the difference were statistically significant(P<0.05),and the application value of the combined test in the diagnosis of T1DM,T2DM was higher than that of single antibody test.Conclusion The combined detection of diabetic autoimmune antibodies can help to better identify the types of diabetes mellitus in clinical practice and provide valuable guidance for subsequent treatment.
万方数据
维普
