The Pathogenic Characteristics and Risk Factors of Nosocomial Infection in Maintenance Dialysis Patients
Objective Objective To explore the pathogenic characteristics and risk factors of nosocomial infection in maintenance dialysis patients in the Department of Nephrology,and to formulate preventive measures.Methods The clinical data of 215 patients with chronic renal failure who underwent maintenance dialysis in the department of nephrology,the First People's Hospital of Tai'an from November 2020 to October 2022 were retrospectively analyzed.Statistics on the occurrence of nosocomial infections of patients were divided into infection group(n=25)and non-infected group(n=190)according to whether the patients had infection.Statistics of infection sites,distribution of pathogenic bacteria and influencing factors.Results 40 strains of pathogens were isolated and cultured,mainly Gram-negative bacteria(55.00%).The results of univariate analysis suggested that PICC,hypoproteinemia,anemia,age,dialysis adequacy,cardiac function and dialysis time were the relevant factors of infection(P<0.05).The results of multivariate analysis showed that PICC(β=1.471,OR=4.352,95%CI 1.520-12.462),hypoproteinemia(β=1.328,OR=3.772,95%CI 1.339-10.630),anemia(β=1.876,OR=6.527,95%CI 2.149-19.826),age≥60 years(β=0.193,OR=1.213,95%CI 0.405-3.628),low dialysis adequacy(β=1.311,OR=0.270,95%CI 0.095-0.764),combined with heart failure(β=1.365,OR=1.255,95%CI 0.087-1.750)and long dialysis time(β=1.286,OR=3.619,95%CI 1.246-10.514)were independent risk factors for nosocomial infection(P<0.05).Conclusion The incidence of nosocomial infection is relatively high in patients receiving maintenance hemodialysis in the department of nephrology,especially respiratory tract infection.The pathogenic bacteria are mainly gram-negative bacteria.The risk factors of patients include hypoproteinemia,no PICC,low dialysis adequacy,anemia,long dialysis time,complicated heart failure,and old age.
万方数据
维普
