The Influence of Cesarean Section History on the Outcome of Artificial Insemination Assisted Pregnancy in Infertile Patients
Objective To analysis the effect of history of cesarean section on the clinical pregnancy rate of artificial insemination.Methods A retrospective analysis was performed on 336 infertile patients with at least one live birth history who received artificial insemination by husband(AIH)treatment at the department of reproductive medicine,Women and Children's Hospital,School of Medicine,Xiamen University,from February 2012 to June 2022,with a total of 560 cycles,including 203 cycles in the cesarean section group and 357 cycles in the other group.Age,BMI,tubal and pelvic factors,history of endometriosis,treatment protocol and pregnancy result were compared in the two groups.Results There were no significant differences in age,senior age(>35 years old),infertility duration,tubal-pelvic factors and history of endometriosis between the two groups.Body mass index(BMI)in cesarean section group was significantly higher than that in vaginal delivery group,(22.30±3.27)kg/m2 and(21.67±2.76)kg/m2,respectively(P<0.05).The proportion of patient's BMI over 23 kg/m2 in cesarean section group was higher than that of the vaginal delivery group,36.9%and 29.7%,respectively,the difference was not statistically significant(P=0.078).The proportion of induced ovulation in cesarean section group was significant higher than that in vaginal delivery group(53.7%vs.44.3%,P<0.05.The clinical pregnancy rate of cesarean section group was 15.3%,and that of vaginal delivery group was 16.5%,the difference was not statistically significant(P=0.853).Conclusion Through appropriate intervention and screening,the clinical pregnancy rate of IUI in women with a history of cesarean section can be improved.
caesarean sectionvaginal deliveryartificial insemination by husbandclinical pregnancy rateovulation inductionbody weight index