Objective To retrospectively analyze the clinical features and prognosis of Klebsiella pneumoniae bloodstream infection in intensive care unit(ICU),and to guide clinical prevention and treatment.Methods The clinical data of 74 patients with Klebsiella pneumoniae bacteremia infection(KP BSI)admitted to the department of ICU of the First Affiliated Hospital of Shandong First Medical University from June 2018 to May 2023 were analyzed.Carbapenem-resistant Klebsiella pneumoniae(CRKP)and carbapenem-susceptible Klebsiella pneumoniae(CSKP)were case-control studies.Results In ICU,CSKP bloodstream infection was mainly primary infection(26/48,54.17%),while CRKP bloodstream infection was mainly caused by pulmonary infection(13/26,50.00%).The 28 d mortality rate was 35.42%(17/48)in the CSKP bloodstream infection group and 61.54%(16/26)in the CRKP bloodstream infection group,the difference was statistically significant(P<0.05).Mechanical ventilation and continuous renal replacement therapy(CRRT)were independent risk factors for 28 d death in KP BSI(OR=27.303,4.697,P<0.05).Conclusion CRKP bloodstream infection is mainly caused by pulmonary infection,with a higher mortality at 28 d.Mechanical ventilation and CRRT are independent risk factors affecting the prognosis of patients.
关键词
重症医学科/肺炎克雷伯菌/血流感染/临床特征/危险因素/预后
Key words
intensive care unit/Klebsiella pneumoniae/bloodstream infection/clinical features/risk factor/prognosis
维普
万方数据