Single Center Multifactorial Analysis of Acute Gangrenous Cholecystitis
Objective To explore the risk factors for acute gangrenous cholecystitis(AGC),and to improve the preoperative diagnosis accuracy of AGC.Methods The reoperative clinical data of 354 patients diagnosed with cholecystitis and treated with surgery in department of hepatobiliary and Pancreatic Surgery,Jinjiang Municipal Hospital from June 2019 to August 2022 were Retrospective analysed,including 52 cases of gangrenous cholecystitis and 302 cases of non gangrenous cholecystitis.Comparing the data differences between the two groups,the different data were brought into the logistic regression equation to determine the main factors affecting the occurrence of acute gangrenous cholecystitis.Results There were significant differences between the two groups in gender,age,body temperature,diabetes,right upper quadrant muscular rigidity,abdominal ultrasound/imaging examination findings gallbladder wall thickness,gallbladder neck calculus impaction,fluid accumulation around gallbladder(P<0.05).Taking the data with differences into the logistic regression equation,it was concluded that age(P=0.007),gallbladder neck calculus impaction(P=0.016),fluid accumulation around gallbladder(P<0.001),were the main factors affecting the occurrence of acute gangrenous cholecystitis.Conclusion Acute gangrenous cholecystitis progresses rapidly,is difficult to diagnose early,and has a high mortality rate.It is necessary to strengthen the understanding of acute gangrenous cholecystitis in clinical practice,and early diagnosis and timely treatment are particularly important.Age,stone entrapment in the neck of the gallbladder,and fluid accumulation around the gallbladder are independent risk factors for gangrenous cholecystitis.