Application of Anterior Intravenous Pump With Dexmedetomidine Induced by General Anesthesia in Elderly Patients Undergoing Hip Surgery
Objective To investigate the effect of anterior venous pump injection of dexmedetomidine induced by general anesthesia in elderly patients undergoing hip surgery.Methods A total of 89 elderly patients with hip surgery admitted to Liwan Central Hospital of Guangzhou from July 2022 to January 2023 were selected as the research objects.According to the random number table method,45 patients were divided into observation group and 44 patients were divided into control group.Patients in the observation group received dexmedetomidine 1.0 µg/kg intravenously 10 min before induction of general anesthesia,while patients in the control group received 0.9％ sodium chloride solution 1.0 µg/kg intravenously 10 min before induction of general anesthesia.The noninvasive cardiac output (NICO),operation time,intraoperative blood loss,intraoperative fluid infusion volume,and adverse reactions were compared between the two groups during the perioperative period[before intravenous infusion of dexmedetomidine or normal saline (T0),after loading dose infusion (T1),at the completion of surgery (T2),1 h after entering the post anesthesia care unit (T3),and 1 day after surgery (T4)].Results NICO of the observation group at T1 and T2 were (4.16±0.34) L/min and (4.39±0.45) L/min,respectively.Stroke volume (SV) were (59.86±10.74) mL,(61.89±8.75) mL,and cardiac index (CI) were (3.46±0.32) min·m2,(3.69±0.37) min·m2 higher than those in the control group,the differences were statistically significant (P<0.05).There was no significant difference in operation time,intraoperative blood loss and fluid infusion between the two groups (P>0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05).Conclusion Intravenous infusion of dexmedetomidine before induction of general anesthesia has little effect on NICO in elderly patients undergoing hip surgery during the perioperative period,and it does not increase the volume of fluid infusion,which is safe.
万方数据
维普
