Observation of the Anesthesia Effect and Cognitive Function Impact of Dexmedetomidine in Patients Andergoing Laparoscopic Cholecystectomy
Objective Exploring the effect of dexmedetomidine on cognitive function in elderly patients undergoing laparoscopic cholecystectomy.Methods A total of 132 elderly patients undergoing cholecystectomy admitted to Jiuquan Second People's Hospital from January 2022 to December 2023 were divided into the observation group (n=66,using dexmedetomidine before anesthesia induction) and a control group (n=66,direct anesthesia induction).The anesthesia effects and their impact on patient cognitive function were compared and observed between the two groups.Results The stability of hemodynamic evaluation indicators in the observation group was significantly better than that in the control group,and the difference was statistically significant (P<0.05).The awakening time,extubation time,and respiratory recovery time of the observation group were (9.26±2.38) min,(12.73±2.84) min,and (9.02±2.67) min,respectively,which were significantly shorter than the control group's (13.07±3.04) min,(14.95±3.16) min,and (11.87±2.75) min,and the differences were statistically significant (P<0.001).The cognitive function scores (20.04±5.19) points and (23.36±4.28) pointsof the observation group patients at 12 and 24 hours after surgery were significantly higher than those of the control group (16.03±5.02) points and (18.54±4.15) points,and the difference was statistically significant (P<0.001).The pain level scores of the observation group at 12 hours and 24 hours after surgery were (4.41±0.68) points and (2.15±0.31) points,which were significantly lower than those of the control group (6.02±0.73) points and (4.37±0.42) points,and the difference was statistically significant (P<0.05).Conclusion In elderly patients undergoing laparoscopic cholecystectomy anesthesia,dexmedetomidine can effectively improve the quality of anesthesia and recovery,and patients have better postoperative cognitive function and lower pain levels.It has significant clinical application value and can provide reference content for the formulation of anesthesia standards for laparoscopic cholecystectomy.
万方数据
维普
