Analysis of the Value of Thromboelastography in the Coagulation Function of Breast Cancer and Benign Breast Lesions
Objective To analyze the clinical detection value of thromboelastography in the coagulation function of breast cancer and benign breast lesions. Methods A total of 55 patients with breast cancer (breast cancer group) and 50 patients with benign breast diseases (benign disease group) admitted to Yangzhou Maternal and Child Health Care Hospital Affiliated to Yangzhou University from June 2022 to December 2023 were selected as research objects. Routine coagulation function indexes and TEG parameters were determined in 2 groups. Results The levels of fibrinogen (Fib),D-dimer (D-D) and blood platelet (PLT) in the breast cancer group were higher than those in the benign disease group,and the prothrombin time (PT) was shorter than that in the benign disease group,the differences were statistically significant (P<0.05). There was no significant difference in thrombin time (TT) and activated partial thromboplastin time (APTT) between the two groups (P>0.05). In breast cancer group,maximum amplitude (MA) was (65.28±7.07) mm,coagulation index (CI) was (2.93±1.32),which were higher than (62.75±5.56) mm and (2.46±1.04) in benign disease group,and the clot formation time (K value) was (1.35±0.32) min,which was shorter than (1.47±0.24) min in benign disease group,the differences were statistically significant (P<0.05). There was no statistical significance in reaction time (R value),Angle angle and shear elastic modulus (G value) between 2 groups (P>0.05). Conclusion In clinical practice,TEG is more sensitive and accurate than conventional coagulation function,and its ability to quickly diagnose coagulation function is of great value for intraoperative and postoperative bleeding management,prevention of deep vein thrombosis,and other aspects.
thromboelastogrambreast cancerbenign breast lesionscoagulation functionparametersclinical value
万方数据
维普
