目的 探讨胸腔镜下肺叶切除术与肺段切除术治疗早期非小细胞肺癌的效果。方法 选择2023年3—12月在枣庄市立医院胸外科以手术进行早期非小细胞肺癌治疗的200例患者为研究对象。以随机数字表法分为对照组与研究组，各100例。对照组采取胸腔镜下肺叶切除术，研究组采取胸腔镜下肺段切除术。对比2组临床效果。结果 研究组住院时间为(5。79±0。71)d，短于对照组的(8。42±1。25)d，差异有统计学意义(P<0。05);研究组手术耗时为(192。64±34。52)min，长于对照组的(147。25±27。46)min，差异有统计学意义(P<0。05);研究组术后引流量、术中失血量分别为(632。18±102。04)mL、(82。05±15。37)mL，少于对照组的(802。96±132。74)mL、(134。07±20。93)mL，差异有统计学意义(P<0。05)。术后，2组第1秒用力呼气容积(forced expiratory volume in the first second，FEV1)、用力肺活量(forced vital capacity，FVC)均低于术前，且研究组均高于对照组，差异有统计学意义(P<0。05)。2组并发症总发生率比较差异无统计学意义(P>0。05)。结论 在早期非小细胞肺癌的治疗中，胸腔镜下肺叶切除术具有更低的手术难度，但胸腔镜下肺段切除术对患者造成的创伤更轻，对患者肺功能影响小。因此，具体应根据患者需要来选择手术。
Effect of Thoracoscopic Lobectomy and Segmentectomy in the Treatment of Early-Stage Non-Small Cell Lung Cancer
Objective To explore the effect of thoracoscopic lobectomy and segmentectomy in the treatment of early-stage non-small cell lung cancer. Methods A total of 200 patients with early-stage non-small cell lung cancer who underwent surgery in the department of thoracic surgery,Zaozhuang Municipal Hospital from March to December 2023 were selected as the research objects. They were divided into control group and study group by random number table method,100 cases in each group. The control group underwent thoracoscopic lobectomy,while the study group received thoracoscopic segmentectomy. The clinical outcomes of both groups were compared. Results The length of hospitalization in the study group was (5.79±0.71) days,which was shorter than (8.42±1.25) days in the control group,the difference was statistically significant (P<0.05). The operation time of the study group was (192.64±34.52) min,which was longer than (147.25±27.46) min of the control group,the difference was statistically significant (P<0.05). The postoperative drainage volume and intraoperative blood loss of the study group were (632.18±102.04) mL and (82.05±15.37) mL,respectively,which were less than (802.96±132.74) mL and (134.07±20.93) mL of the control group,the differences were statistically significant (P<0.05). After operation,forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC) in 2 groups were lower than before operation,and the study group was higher than the control group,the differences were statistically significant (P<0.05). There was no significant difference in the total incidence of complications between the two groups (P>0.05). Conclusion While thoracoscopic lobectomy presents lower surgical complexity in the treatment of early-stage non-small cell lung cancer,thoracoscopic segmentectomy is associated with less trauma and a reduced impact on lung function. Therefore,the choice of procedure should be tailored to the individual needs of each patient.
thoracoscopylobectomysegmentectomyearly-stage non-small cell lung cancertherapeutic effectpulmonary function
万方数据
维普
