Clinical Efficacy of Propafenone Hydrochloride Tablets and Amiodarone in the Treatment of Arrhythmia and Their Impact on Cardiac Function
Objective To explore the application effects of using propafenone hydrochloride tablets and amiodarone in the treatment of arrhythmia and their impact on patients' cardiac function. Methods A total of 108 patients with arrhythmia enrolled in the department of cardiovascular medicine,Zhangzhou Affiliated Hospital of Fujian Medical University from January 2021 to October 2023 were selected and divided into the control group and observation group with 54 patients in each group by random number table method. The control group was treated with propafenone hydrochloride tablets,and the observation group was treated with amiodarone. The application effect was discussed. Results The total effective rate of the observation group was 100％,higher than 87.04％ of the control group,and the difference was statistically significant (P<0.05). After treatment,left ventricular ejection fraction (LVEF) in the two groups was higher than before treatment,and left ventricular end-systolic diameter (LVESD),left ventricular end-diastolic diameter (LVEDD) were lower than before treatment,the differences were statistically significant (P<0.05). LVEF of the observation group was (53.02±2.12)％,which was higher than (44.85±1.62)％ of the control group,LVEDD and LVESD of the observation group were (42.52±2.11) mm and (35.96±1.26) mm,respectively,which were lower than (54.11±2.35) mm and (43.11±1.44) mm of the control group,and the differences were statistically significant (P<0.05). The pre-ventricular contraction,pre-atrial contraction and pre-atrioventricular junction contraction in 2 groups were lower than before treatment,and the differences were statistically significant (P<0.05). The pre-ventricular contraction,pre-atrial contraction and pre-atrioventricular junction contraction in observation group were lower than those in control group,and the differences were statistically significant (P<0.05). The scores of physiological function,social function,emotional function and mental health in 2 groups were higher than before treatment,and the differences were statistically significant (P<0.05). The scores of physiological function,social function,emotional function and mental health in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05). The total satisfaction of the observation group was 98.15％,higher than 83.33％ of the control group,and the difference was statistically significant (P<0.05). Conclusion The application effect of amiodarone in the treatment of arrhythmia is better than that of propafenone hydrochloride tablets. It can not only improve patients' cardiac function indicators and arrhythmia indicators,improve their life scores and treatment satisfaction,improve prognosis.
arrhythmiapropafenone hydrochloride tabletsamiodaroneheart functionquality of lifesatisfaction
万方数据
维普
