Effect of Carboprost Tromethamine Combined With Cervical Pull-Up Suture on Placenta Previa Bleeding
Objective To investigate the effect of carprost trochantriol combined with cervical pull-up suture in women with refractory postpartum hemorrhage during placenta previa cesarean section. Methods A total of 60 women diagnosed with placenta previa and refractory postpartum hemorrhage during cesarean section admitted to Dalang Hospital of Dongguan from January 2022 to December 2023 were selected as the study objects. According to the random number table method,they were divided into observation group and control group,30 cases in each group.The observation group was treated with oxytocin,carboprost tromethamine combined with cervical pull-up suture,and the control group was treated with oxytocin combined with ligation of the descending branch of uterine artery. The intraoperative and postoperative bleeding volume,clinical therapeutic effect,changes in coagulation function indexes such as fibrinogen (FIB) and D-dimer (D-D) and the occurrence of complications were compared between the two groups. Results The bleeding volume at 2,12 and 24 h after operation in the observation group were (674.33±35.37) mL,(908.22±42.24) mL and (1003.24±43.47) mL,respectively,which were lower than (753.63±40.62) mL,(1110.87±51.15) mL and (1124.54±60.28) mL in the control group,the differences were statistically significant (P<0.05). At 24 h after operation,D-D and FIB indexes in observation group were lower than those in control group,the differences were statistically significant (P<0.05). The total effective rate of treatment in the observation group was 93.33％,which was higher than 73.33％ in the control group,the difference was statistically significant (P<0.05). There were no cases of hysterectomy in both groups. The total incidence rate of complications in the observation group was 6.67％,which was lower than 26.67％ in the control group,the difference was statistically significant (P<0.05). Conclusion Providing carboprost tromethamine combined with cervical pull-up suture for the treatment of refractory postpartum hemorrhage in cesarean section with placenta previa can reduce postpartum hemorrhage,improve hemostatic efficacy,reduce incidence of complications,improve coagulation function indicators,and promote faster postpartum recovery.
carboprost tromethaminecervical pull-up sutureplacental previarefractory postpartum hemorrhagecesarean sectioncoagulation function
万方数据
维普
