Effects of Different Proportions of Self-Made Yuzhu Oral Spray on Saliva Flow Rate of Healthy Volunteers
Objective To observe the effect of different proportions of Yuzhu water decoction oral spray on the saliva secretion of healthy volunteers,and compare its effect with the basic saliva flow rate,so as to confirm the best proportion of Yuzhu water decoction oral spray. Methods A total of 80 medical staff from Zhongshan Hospital Xiamen University were selected as health volunteers from April to September 2022. The patients were divided into high concentration group (12:200),medium concentration group (9:200),low concentration group (6:200) and sterilized water group with 20 participants each by simple randomization method. The corresponding concentration of spray intervention was carried out,and the average value of static saliva flow rate of 5 min before and after the intervention of 80 subjects,and the difference of saliva flow rate between different concentration groups and sterilized water group were compared. Results The salivary flow rates after intervention for the high concentration group,medium concentration group,low concentration group,and sterile water group were (0.29±0.08) mL/min,(0.25±0.10) mL/min,(0.23±0.10) mL/min,and (0.22±0.13) mL/min,there was no significant difference (P>0.05). The difference of saliva flow rates for the high concentration group,medium concentration group,low concentration group,and sterile water group were (-0.12±0.06) mL/min,(-0.08±0.03) mL/min,(-0.06±0.03) mL/min,and (-0.05±0.02) mL/min,the difference of saliva flow rates of the 4 groups was compared,and the difference was statistically significant (P<0.05),among which the difference of saliva flow rate of the high concentration group was compared with that of the medium concentration group,the low concentration group and the sterilized water group,the difference was statistically significant (P<0.05). Conclusion The high concentration of Yuzhu water decoction spray can improve the salivary flow rate,relieve thirst,and provide a new theoretical basis for relieving thirst symptoms.
万方数据
维普
