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健康体检人群幽门螺杆菌感染情况及其影响因素分析

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目的 分析健康体检人群中幽门螺杆菌(Helicobacter pylori,Hp)的感染情况及其影响因素。方法 回顾性分析2022 年 1-5 月在新疆医科大学第一附属医院健康管理中心体检的 7 899 名体检者Hp感染情况。均进行碳 13 呼气试验,根据检测结果分为Hp阳性组与Hp阴性组。比较 2 组一般情况、血糖、血脂等指标,采用多因素logistic回归分析Hp感染情况及其影响因素。结果 在 7 899 名研究对象中,检测出Hp阳性 2 658 例,占比为 33。65%。其中女性感染率高于男性;18~45 岁感染率最高,为 50。75%。2 组年龄、性别、吸烟史、身体质量指数(body mass index,BMI)、尿酸、总胆固醇(total cholesterol,TC)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)比较,差异有统计学意义(P<0。05)。多因素logistic回归分析结果显示,女性、肥胖、超重、有吸烟史、尿酸升高是感染Hp的独立影响因素(P<0。05)。结论 新疆医科大学第一附属医院健康管理中心体检者Hp感染率低于国内平均水平,女性、肥胖、超重、有吸烟史、尿酸升高为健康体检人群感染Hp的影响因素。
Analysis of Helicobacter Pylori Infection and Its Influencing Factors in Healthy Physical Examination Population
Objective To analyze the status of Helicobacter pylori(Hp)infection and its influencing factors in healthy physical examination population.Methods The Hp infection of 7 899 physical examinees in the health management center,the First Affiliated Hospital of Xinjiang Medical University from January to May 2022 was analyzed retrospectively.All of them underwent carbon 13 breath test,and were divided into Hp positive group and Hp negative group according to the test results.The general situation,blood sugar,blood lipid and other indicators were compared between the two groups,and multiple logistic regression analysis was further carried out to analyze Hp infection and its influencing factors.Results Among 7 899 subjects,2 658 cases were Hp positive,accounting for 33.65%.The infection rate of females was higher than that of males.The highest infection rate was 50.75%at the age of 18 to 45.The age,sex,smoking history,body mass index(BMI),uric acid,total cholesterol(TC),high density lipoprotein cholesterol(HDL-C)between the two groups were statistically significant(P<0.05).Multivariate logistic regression analysis showed that female,obesity,overweight,smoking history and elevated uric acid were the independent influencing factors of Hp infection(P<0.05).Conclusion The Hp infection rate in the health management center,the First Affiliated Hospital of Xinjiang Medical University is lower than the average level in China.Female,obesity,overweight,smoking history and elevated uric acid are the influencing factors of Hp infection in healthy people.

Helicobacter pyloridyslipidemiaphysical examinationinfluencing factorstatus of infectionmetabolic factors

布尔列妮·吾力加别克、杨晓萍

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新疆医科大学第一附属医院健康管理中心,新疆 乌鲁木齐 830054

幽门螺杆菌 血脂异常 体检人群 影响因素 感染情况 代谢因素

2024

中国卫生标准管理
《中国卫生标准管理》杂志社

中国卫生标准管理

影响因子:1.374
ISSN:1674-9316
年,卷(期):2024.15(23)