Clinical Effect and Safety Analysis of Fire Needle in the Treatment of Pruritus Skin Disease
Objective To analyze the clinical effect and safety of fire needle in the treatment of pruritus skin disease.Methods A total of 50 patients with pruritus skin disease admitted to the department of rehabilitation medicine,the First Hospital of Putian City from November 2021 to January 2023 were selected as the research subjects.They were randomly divided into the fire needle intervention group and the non fire needle intervention group according to different treatment methods,with 25 cases in each group.The non fire needle intervention group was given dexamethasone combined with compound borneol calamine antibacterial lotion,and the fire needle intervention group was given fire needle treatment on the basis of the non fire needle intervention group.The clinical efficacy,itching degree,skin lesion symptom score,inflammatory factor levels,and incidence of adverse reactions of two groups were compared.Results The total effective rate of the fire needle intervention group was 96.00%(24/25),which was higher than 68.00%(17/25)of the non fire needle intervention group,the difference was statistically significant(P<0.05).After 1 and 4 weeks of treatment,the itching degree scores of the fire needle intervention group were(1.42±0.19)points and(0.34±0.03)points,which were lower than(1.68±0.21)points and(1.10±0.14)points of the non fire needle intervention group,the differences were statistically significant(P<0.05).After 1 and 4 weeks of treatment,severity scoring of atopic dermatitis(SCORAD)scores of the fire needle intervention group were(35.57±4.68)points and(15.33±3.59)points,respectively,which were lower than(42.82±6.22)points and(21.75±4.96)points of the non fire needle intervention group,the differences were statistically significant(P<0.05).After 4 weeks of treatment,tumor necrosis factor-α(TNF-α),interleukin-4(IL-4)and procalcitonin(PCT)of the fire needle intervention group were(2.89±0.64)pg/mL,(2.99±0.58)ng/L,and(2.39±0.34)µg/L,respectively,which were lower than(4.31±0.88)pg/mL,(4.31±0.75)ng/L,(3.37±0.25)µg/L of the non fire needle intervention group,the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the fire needle intervention group was 0,which was lower than 24.00%in the non fire needle intervention group,the difference was statistically significant(P<0.05).Conclusion The clinical effect of fire needle treatment on pruritus skin disease is significant,relieving the degree of itching,improving skin lesion symptoms,controlling inflammatory factor levels,and its safety is good.
万方数据
维普
